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Paediatric scrub typhus in Thailand: a study of 73 confirmed cases.
Trans R Soc Trop Med Hyg 2004; 98(6):354-9TR

Abstract

We studied 73 Thai children with scrub typhus (median age 9 years, range 3-14 years, male:female ratio 1.8:1). Most patients (86%) lived in rural areas. They presented with subacute fever (median, 9 d) with vomiting (35%), hepatomegaly (59%), splenomegaly (18%), and tachypnea (26%). Skin rash (7%), eschar (7%), and history of mite bite were rare. Blood leucocyte counts were usually normal but 19% of patients were thrombocytopenic. Twenty (22%) patients had pneumonia and six (8%) had neurological involvement. Defervescence occurred a median of 1 d and 3 d after initiation of doxycycline and chloramphenicol, respectively, and these responses were more rapid than in those who received other antibiotics or no treatment (P < 0.001). There was one death. Only 55% of the patients were initially diagnosed as having scrub typhus.

Authors+Show Affiliations

Department of Paediatrics, Hat-yai Hospital, Hat-yai, Songkla, Thailand.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15099991

Citation

Silpapojakul, Kamkarn, et al. "Paediatric Scrub Typhus in Thailand: a Study of 73 Confirmed Cases." Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 98, no. 6, 2004, pp. 354-9.
Silpapojakul K, Varachit B, Silpapojakul K. Paediatric scrub typhus in Thailand: a study of 73 confirmed cases. Trans R Soc Trop Med Hyg. 2004;98(6):354-9.
Silpapojakul, K., Varachit, B., & Silpapojakul, K. (2004). Paediatric scrub typhus in Thailand: a study of 73 confirmed cases. Transactions of the Royal Society of Tropical Medicine and Hygiene, 98(6), pp. 354-9.
Silpapojakul K, Varachit B, Silpapojakul K. Paediatric Scrub Typhus in Thailand: a Study of 73 Confirmed Cases. Trans R Soc Trop Med Hyg. 2004;98(6):354-9. PubMed PMID: 15099991.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Paediatric scrub typhus in Thailand: a study of 73 confirmed cases. AU - Silpapojakul,Kamkarn, AU - Varachit,Boonyarat, AU - Silpapojakul,Khachornsakdi, PY - 2003/06/03/received PY - 2003/10/27/revised PY - 2003/10/29/accepted PY - 2004/4/22/pubmed PY - 2004/7/13/medline PY - 2004/4/22/entrez SP - 354 EP - 9 JF - Transactions of the Royal Society of Tropical Medicine and Hygiene JO - Trans. R. Soc. Trop. Med. Hyg. VL - 98 IS - 6 N2 - We studied 73 Thai children with scrub typhus (median age 9 years, range 3-14 years, male:female ratio 1.8:1). Most patients (86%) lived in rural areas. They presented with subacute fever (median, 9 d) with vomiting (35%), hepatomegaly (59%), splenomegaly (18%), and tachypnea (26%). Skin rash (7%), eschar (7%), and history of mite bite were rare. Blood leucocyte counts were usually normal but 19% of patients were thrombocytopenic. Twenty (22%) patients had pneumonia and six (8%) had neurological involvement. Defervescence occurred a median of 1 d and 3 d after initiation of doxycycline and chloramphenicol, respectively, and these responses were more rapid than in those who received other antibiotics or no treatment (P < 0.001). There was one death. Only 55% of the patients were initially diagnosed as having scrub typhus. SN - 0035-9203 UR - https://www.unboundmedicine.com/medline/citation/15099991/Paediatric_scrub_typhus_in_Thailand:_a_study_of_73_confirmed_cases_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S003592030400029X DB - PRIME DP - Unbound Medicine ER -