Kumada-Corriu reactions of alkyl halides with alkynyl nucleophiles.
Org Lett. 2004 Apr 29; 6(9):1461-3.OL

Abstract

[reaction: see text] Pd(2)(dba)(3)-Ph(3)P-catalyzed Kumada-Corriu coupling reactions of unactivated alkyl bromides or iodides with an alkynyl nucleophile furnish C(sp)-C(sp)3 bond formation. Alkynyl nucleophiles can be alkynyllithiums or the corresponding Grignard reagents. The superior performance of Ph(3)P ligand over the trialkylphosphine ligands indicates that this cross-coupling reaction may be a reductive-elimination-controlled process.

Authors+Show Affiliations

Yang LM

Department of Chemistry and Institute of Polymer Science and Engineering, National Taiwan University, Taipei, Taiwan.

Huang LF

No affiliation info available

Luh TY

No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15101767

Citation

Yang, Lian-Ming, et al. "Kumada-Corriu Reactions of Alkyl Halides With Alkynyl Nucleophiles." Organic Letters, vol. 6, no. 9, 2004, pp. 1461-3.

Yang LM, Huang LF, Luh TY. Kumada-Corriu reactions of alkyl halides with alkynyl nucleophiles. Org Lett. 2004;6(9):1461-3.

Yang, L. M., Huang, L. F., & Luh, T. Y. (2004). Kumada-Corriu reactions of alkyl halides with alkynyl nucleophiles. Organic Letters, 6(9), 1461-3.

Yang LM, Huang LF, Luh TY. Kumada-Corriu Reactions of Alkyl Halides With Alkynyl Nucleophiles. Org Lett. 2004 Apr 29;6(9):1461-3. PubMed PMID: 15101767.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Kumada-Corriu reactions of alkyl halides with alkynyl nucleophiles. AU - Yang,Lian-Ming, AU - Huang,Li-Fu, AU - Luh,Tien-Yau, PY - 2004/4/23/pubmed PY - 2004/4/23/medline PY - 2004/4/23/entrez SP - 1461 EP - 3 JF - Organic letters JO - Org Lett VL - 6 IS - 9 N2 - [reaction: see text] Pd(2)(dba)(3)-Ph(3)P-catalyzed Kumada-Corriu coupling reactions of unactivated alkyl bromides or iodides with an alkynyl nucleophile furnish C(sp)-C(sp)3 bond formation. Alkynyl nucleophiles can be alkynyllithiums or the corresponding Grignard reagents. The superior performance of Ph(3)P ligand over the trialkylphosphine ligands indicates that this cross-coupling reaction may be a reductive-elimination-controlled process. SN - 1523-7060 UR - https://www.unboundmedicine.com/medline/citation/15101767/Kumada_Corriu_reactions_of_alkyl_halides_with_alkynyl_nucleophiles_ DB - PRIME DP - Unbound Medicine ER -

Tags

Kumada-Corriu reactions of alkyl halides with alkynyl nucleophiles.Org Lett. 2004 Apr 29; 6(9):1461-3.OL