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The clinical significance of measles: a review.
J Infect Dis. 2004 May 01; 189 Suppl 1:S4-16.JI

Abstract

Forty years after effective vaccines were licensed, measles continues to cause death and severe disease in children worldwide. Complications from measles can occur in almost every organ system. Pneumonia, croup, and encephalitis are common causes of death; encephalitis is the most common cause of long-term sequelae. Measles remains a common cause of blindness in developing countries. Complication rates are higher in those <5 and >20 years old, although croup and otitis media are more common in those <2 years old and encephalitis in older children and adults. Complication rates are increased by immune deficiency disorders, malnutrition, vitamin A deficiency, intense exposures to measles, and lack of previous measles vaccination. Case-fatality rates have decreased with improvements in socioeconomic status in many countries but remain high in developing countries.

Authors+Show Affiliations

National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

15106083

Citation

Perry, Robert T., and Neal A. Halsey. "The Clinical Significance of Measles: a Review." The Journal of Infectious Diseases, vol. 189 Suppl 1, 2004, pp. S4-16.
Perry RT, Halsey NA. The clinical significance of measles: a review. J Infect Dis. 2004;189 Suppl 1:S4-16.
Perry, R. T., & Halsey, N. A. (2004). The clinical significance of measles: a review. The Journal of Infectious Diseases, 189 Suppl 1, S4-16.
Perry RT, Halsey NA. The Clinical Significance of Measles: a Review. J Infect Dis. 2004 May 1;189 Suppl 1:S4-16. PubMed PMID: 15106083.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The clinical significance of measles: a review. AU - Perry,Robert T, AU - Halsey,Neal A, PY - 2004/4/24/pubmed PY - 2004/6/16/medline PY - 2004/4/24/entrez SP - S4 EP - 16 JF - The Journal of infectious diseases JO - J. Infect. Dis. VL - 189 Suppl 1 N2 - Forty years after effective vaccines were licensed, measles continues to cause death and severe disease in children worldwide. Complications from measles can occur in almost every organ system. Pneumonia, croup, and encephalitis are common causes of death; encephalitis is the most common cause of long-term sequelae. Measles remains a common cause of blindness in developing countries. Complication rates are higher in those <5 and >20 years old, although croup and otitis media are more common in those <2 years old and encephalitis in older children and adults. Complication rates are increased by immune deficiency disorders, malnutrition, vitamin A deficiency, intense exposures to measles, and lack of previous measles vaccination. Case-fatality rates have decreased with improvements in socioeconomic status in many countries but remain high in developing countries. SN - 0022-1899 UR - https://www.unboundmedicine.com/medline/citation/15106083/full_citation L2 - https://academic.oup.com/jid/article-lookup/doi/10.1086/377712 DB - PRIME DP - Unbound Medicine ER -