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Ultrasound-guided fine-needle aspiration biopsy remains a valid approach in the evaluation of nonpalpable breast lesions.
Diagn Cytopathol. 2004 May; 30(5):325-31.DC

Abstract

The use of ultrasound-guided fine-needle aspiration (FNA) biopsy for nonpalpable breast lesions varies considerably. This retrospective study stresses the role of breast FNA in evaluating sonographically suspicious nonpalpable breast masses using a probabilistic reporting system. One hundred and eight consecutive ultrasound-guided FNA biopsies diagnosed as positive (32), suspicious (8), atypical (11), benign (55), and unsatisfactory (2) were analyzed and correlated with 61 subsequent surgical specimens. All positive cytologies showed carcinoma on histology; suspicious cases were followed by 5 carcinomas, 2 fibroadenomas, and 1 papillary lesion. Follow-up of atypical cases included 4 carcinomas, 3 fibroadenomas, and 2 papillary lesions, while all 10 biopsies following benign cytology showed fibrocystic changes. Two cases with suspicious sonographic findings but unsatisfactory cytology had lobular carcinoma. The remainder of the benign and atypical cases were followed clinically and radiographically for at least 10 months and had no evidence of carcinoma. Positive predictive values were positive, 100%; suspicious, 63%; atypical, 36%; benign, 0%. Most (40/43; 93%) carcinomas were invasive. In conclusion, ultrasound-guided FNA for nonpalpable breast lesions is highly accurate, and probabilistic reporting helps direct patient management.

Authors+Show Affiliations

Department of Pathology and Laboratory Medicine, University of Kentucky Medical Center, Lexington, Kentucky, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15108230

Citation

Liao, Jim, et al. "Ultrasound-guided Fine-needle Aspiration Biopsy Remains a Valid Approach in the Evaluation of Nonpalpable Breast Lesions." Diagnostic Cytopathology, vol. 30, no. 5, 2004, pp. 325-31.
Liao J, Davey DD, Warren G, et al. Ultrasound-guided fine-needle aspiration biopsy remains a valid approach in the evaluation of nonpalpable breast lesions. Diagn Cytopathol. 2004;30(5):325-31.
Liao, J., Davey, D. D., Warren, G., Davis, J., Moore, A. R., & Samayoa, L. M. (2004). Ultrasound-guided fine-needle aspiration biopsy remains a valid approach in the evaluation of nonpalpable breast lesions. Diagnostic Cytopathology, 30(5), 325-31.
Liao J, et al. Ultrasound-guided Fine-needle Aspiration Biopsy Remains a Valid Approach in the Evaluation of Nonpalpable Breast Lesions. Diagn Cytopathol. 2004;30(5):325-31. PubMed PMID: 15108230.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ultrasound-guided fine-needle aspiration biopsy remains a valid approach in the evaluation of nonpalpable breast lesions. AU - Liao,Jim, AU - Davey,Diane D, AU - Warren,Graham, AU - Davis,Joseph, AU - Moore,Angela R, AU - Samayoa,Luis M, PY - 2004/4/27/pubmed PY - 2005/5/19/medline PY - 2004/4/27/entrez SP - 325 EP - 31 JF - Diagnostic cytopathology JO - Diagn Cytopathol VL - 30 IS - 5 N2 - The use of ultrasound-guided fine-needle aspiration (FNA) biopsy for nonpalpable breast lesions varies considerably. This retrospective study stresses the role of breast FNA in evaluating sonographically suspicious nonpalpable breast masses using a probabilistic reporting system. One hundred and eight consecutive ultrasound-guided FNA biopsies diagnosed as positive (32), suspicious (8), atypical (11), benign (55), and unsatisfactory (2) were analyzed and correlated with 61 subsequent surgical specimens. All positive cytologies showed carcinoma on histology; suspicious cases were followed by 5 carcinomas, 2 fibroadenomas, and 1 papillary lesion. Follow-up of atypical cases included 4 carcinomas, 3 fibroadenomas, and 2 papillary lesions, while all 10 biopsies following benign cytology showed fibrocystic changes. Two cases with suspicious sonographic findings but unsatisfactory cytology had lobular carcinoma. The remainder of the benign and atypical cases were followed clinically and radiographically for at least 10 months and had no evidence of carcinoma. Positive predictive values were positive, 100%; suspicious, 63%; atypical, 36%; benign, 0%. Most (40/43; 93%) carcinomas were invasive. In conclusion, ultrasound-guided FNA for nonpalpable breast lesions is highly accurate, and probabilistic reporting helps direct patient management. SN - 8755-1039 UR - https://www.unboundmedicine.com/medline/citation/15108230/Ultrasound_guided_fine_needle_aspiration_biopsy_remains_a_valid_approach_in_the_evaluation_of_nonpalpable_breast_lesions_ L2 - https://doi.org/10.1002/dc.20068 DB - PRIME DP - Unbound Medicine ER -