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The pentose phosphate pathway in Trypanosoma cruzi.
FEMS Microbiol Lett. 2004 May 01; 234(1):117-23.FM

Abstract

The pentose phosphate pathway has been studied in Trypanosoma cruzi, Clone CL Brener. Functioning of the pathway was demonstrated in epimastigotes by measuring the evolution of (14)CO(2) from [1-(14)C] or [6-(14)C]D-glucose. Glucose consumption through the PPP increased from 9.9% to 20.4% in the presence of methylene blue, which mimics oxidative stress. All the enzymes of the PPP are present in the four major developmental stages of the parasite. Subcellular localisation experiments suggested that the PPP enzymes have a cytosolic component, predominant in most cases, although all of them also seem to have organellar localisation(s).

Authors+Show Affiliations

Instituto de Investigaciones Biotecnologicas/INTECH, Universidad Nacional de General San Martin/CONICET, Av. Gral Paz s/n, INTI, edificio 24, Av. General Paz y Albarellos, Casilla de Correo 30, 1650 San Martin, Buenos Aires, Argentina.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15109729

Citation

Maugeri, Dante A., and Juan J. Cazzulo. "The Pentose Phosphate Pathway in Trypanosoma Cruzi." FEMS Microbiology Letters, vol. 234, no. 1, 2004, pp. 117-23.
Maugeri DA, Cazzulo JJ. The pentose phosphate pathway in Trypanosoma cruzi. FEMS Microbiol Lett. 2004;234(1):117-23.
Maugeri, D. A., & Cazzulo, J. J. (2004). The pentose phosphate pathway in Trypanosoma cruzi. FEMS Microbiology Letters, 234(1), 117-23.
Maugeri DA, Cazzulo JJ. The Pentose Phosphate Pathway in Trypanosoma Cruzi. FEMS Microbiol Lett. 2004 May 1;234(1):117-23. PubMed PMID: 15109729.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The pentose phosphate pathway in Trypanosoma cruzi. AU - Maugeri,Dante A, AU - Cazzulo,Juan J, PY - 2003/12/29/received PY - 2004/03/03/revised PY - 2004/03/08/accepted PY - 2004/4/28/pubmed PY - 2004/8/24/medline PY - 2004/4/28/entrez SP - 117 EP - 23 JF - FEMS microbiology letters JO - FEMS Microbiol. Lett. VL - 234 IS - 1 N2 - The pentose phosphate pathway has been studied in Trypanosoma cruzi, Clone CL Brener. Functioning of the pathway was demonstrated in epimastigotes by measuring the evolution of (14)CO(2) from [1-(14)C] or [6-(14)C]D-glucose. Glucose consumption through the PPP increased from 9.9% to 20.4% in the presence of methylene blue, which mimics oxidative stress. All the enzymes of the PPP are present in the four major developmental stages of the parasite. Subcellular localisation experiments suggested that the PPP enzymes have a cytosolic component, predominant in most cases, although all of them also seem to have organellar localisation(s). SN - 0378-1097 UR - https://www.unboundmedicine.com/medline/citation/15109729/The_pentose_phosphate_pathway_in_Trypanosoma_cruzi_ L2 - https://academic.oup.com/femsle/article-lookup/doi/10.1016/j.femsle.2004.03.018 DB - PRIME DP - Unbound Medicine ER -