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Kava Hepatotoxicity: Are we any closer to the truth?
Planta Med. 2004 Mar; 70(3):193-6.PM

Abstract

In recent years, kava kava (Piper methysticum, Forst. f., Piperaceae) has been implicated in a number of liver failure cases. Ever since this has kept the scientific world busy. Even though, on closer inspection, the majority of the case reports are probably not connected to kava intake, hepatotoxic effects of kava cannot generally be ruled out. In this article the major theories as to the mechanism of kava hepatotoxicity are summarized. But in spite of all these hypotheses, there is still no satisfactory answer. In any case, further studies, that might hopefully restore the reputation of kava, are required.

Authors+Show Affiliations

University of Sydney, NSW, Australia.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15114493

Citation

Anke, Jennifer, and Iqbal Ramzan. "Kava Hepatotoxicity: Are We Any Closer to the Truth?" Planta Medica, vol. 70, no. 3, 2004, pp. 193-6.
Anke J, Ramzan I. Kava Hepatotoxicity: Are we any closer to the truth? Planta Med. 2004;70(3):193-6.
Anke, J., & Ramzan, I. (2004). Kava Hepatotoxicity: Are we any closer to the truth? Planta Medica, 70(3), 193-6.
Anke J, Ramzan I. Kava Hepatotoxicity: Are We Any Closer to the Truth. Planta Med. 2004;70(3):193-6. PubMed PMID: 15114493.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Kava Hepatotoxicity: Are we any closer to the truth? AU - Anke,Jennifer, AU - Ramzan,Iqbal, PY - 2004/4/29/pubmed PY - 2004/8/10/medline PY - 2004/4/29/entrez SP - 193 EP - 6 JF - Planta medica JO - Planta Med VL - 70 IS - 3 N2 - In recent years, kava kava (Piper methysticum, Forst. f., Piperaceae) has been implicated in a number of liver failure cases. Ever since this has kept the scientific world busy. Even though, on closer inspection, the majority of the case reports are probably not connected to kava intake, hepatotoxic effects of kava cannot generally be ruled out. In this article the major theories as to the mechanism of kava hepatotoxicity are summarized. But in spite of all these hypotheses, there is still no satisfactory answer. In any case, further studies, that might hopefully restore the reputation of kava, are required. SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/15114493/Kava_Hepatotoxicity:_Are_we_any_closer_to_the_truth L2 - https://www.thieme-connect.com/DOI/DOI?10.1055/s-2004-815533 DB - PRIME DP - Unbound Medicine ER -