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Relationship between environmental tobacco smoke and urinary cotinine levels in passive smokers at their residence.
J Expo Anal Environ Epidemiol 2004; 14 Suppl 1:S65-70JE

Abstract

Studies of the health effects of environmental tobacco smoke (ETS) using measured air concentrations are subject to bias. Cotinine, a nicotine metabolite detected in urine, has been recommended as a quantitative measure of nicotine intake and thus as a marker for ETS exposure in humans. The aim of this study was to correlate home indoor ETS levels with passive smokers' urinary cotinine levels. The urinary cotinine concentrations of 57 non-smoking women who spend >19 h a day at home and the nicotine levels in their living room air were measured over a period of 24 h. Nicotine and urinary cotinine levels were analyzed using GC/MS and HPLC/UV, respectively. In addition, information was collected regarding the smoking habits of the subjects' families. A significant correlation was found between the nicotine levels in indoor air and the urinary cotinine to creatinine ratio of the passive smokers. The smoking habits of the subjects' family members were also correlated to the urinary cotinine levels of the passive smokers.

Authors+Show Affiliations

The Graduate School of Health Science and Management, Yonsei University, Seoul, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15118747

Citation

Kim, Hyojin, et al. "Relationship Between Environmental Tobacco Smoke and Urinary Cotinine Levels in Passive Smokers at Their Residence." Journal of Exposure Analysis and Environmental Epidemiology, vol. 14 Suppl 1, 2004, pp. S65-70.
Kim H, Lim Y, Lee S, et al. Relationship between environmental tobacco smoke and urinary cotinine levels in passive smokers at their residence. J Expo Anal Environ Epidemiol. 2004;14 Suppl 1:S65-70.
Kim, H., Lim, Y., Lee, S., Park, S., Kim, C., Hong, C., & Shin, D. (2004). Relationship between environmental tobacco smoke and urinary cotinine levels in passive smokers at their residence. Journal of Exposure Analysis and Environmental Epidemiology, 14 Suppl 1, pp. S65-70.
Kim H, et al. Relationship Between Environmental Tobacco Smoke and Urinary Cotinine Levels in Passive Smokers at Their Residence. J Expo Anal Environ Epidemiol. 2004;14 Suppl 1:S65-70. PubMed PMID: 15118747.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relationship between environmental tobacco smoke and urinary cotinine levels in passive smokers at their residence. AU - Kim,Hyojin, AU - Lim,Youngwook, AU - Lee,Seokju, AU - Park,Soungeun, AU - Kim,Changsoo, AU - Hong,Cheinsoo, AU - Shin,Dongchun, PY - 2004/5/1/pubmed PY - 2004/7/9/medline PY - 2004/5/1/entrez SP - S65 EP - 70 JF - Journal of exposure analysis and environmental epidemiology JO - J Expo Anal Environ Epidemiol VL - 14 Suppl 1 N2 - Studies of the health effects of environmental tobacco smoke (ETS) using measured air concentrations are subject to bias. Cotinine, a nicotine metabolite detected in urine, has been recommended as a quantitative measure of nicotine intake and thus as a marker for ETS exposure in humans. The aim of this study was to correlate home indoor ETS levels with passive smokers' urinary cotinine levels. The urinary cotinine concentrations of 57 non-smoking women who spend >19 h a day at home and the nicotine levels in their living room air were measured over a period of 24 h. Nicotine and urinary cotinine levels were analyzed using GC/MS and HPLC/UV, respectively. In addition, information was collected regarding the smoking habits of the subjects' families. A significant correlation was found between the nicotine levels in indoor air and the urinary cotinine to creatinine ratio of the passive smokers. The smoking habits of the subjects' family members were also correlated to the urinary cotinine levels of the passive smokers. SN - 1053-4245 UR - https://www.unboundmedicine.com/medline/citation/15118747/Relationship_between_environmental_tobacco_smoke_and_urinary_cotinine_levels_in_passive_smokers_at_their_residence_ L2 - http://dx.doi.org/10.1038/sj.jea.7500360 DB - PRIME DP - Unbound Medicine ER -