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Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre.
J Ethnopharmacol. 2004 Apr; 91(2-3):237-42.JE

Abstract

Methanolic extracts from the heart wood, stem bark, and stem wood of Ventilago harmandiana Pierre (Family Rhamnaceae) were assessed for anti-inflammatory effects using both acute and chronic inflammatory models. Analgesic and antipyretic activities of the extracts were also evaluated. It was found that all extracts possessed strong inhibitory effects on the acute phase of inflammation as seen in ethyl phenylpropiolate (EPP)- and arachidonic acid (AA)-induced ear edema as well as in carrageenin-induced paw edema in rats. The extracts elicited only weak inhibitory activity on cotton pellet-induced granuloma formation, a subchronic inflammatory model. In the analgesic test, all extracts exerted pronounced inhibitory activity in acetic acid-induced writhing response but showed only weak effects in the tail-flick test. The extracts also showed excellent antipyretic activity on yeast-induced hyperthermia in rats.

Authors+Show Affiliations

Department of Pharmacology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. apanthon@med.cmu.ac.thNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15120445

Citation

Panthong, Ampai, et al. "Anti-inflammatory Activity of Methanolic Extracts From Ventilago Harmandiana Pierre." Journal of Ethnopharmacology, vol. 91, no. 2-3, 2004, pp. 237-42.
Panthong A, Kanjanapothi D, Taesotikul T, et al. Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre. J Ethnopharmacol. 2004;91(2-3):237-42.
Panthong, A., Kanjanapothi, D., Taesotikul, T., Phankummoon, A., Panthong, K., & Reutrakul, V. (2004). Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre. Journal of Ethnopharmacology, 91(2-3), 237-42.
Panthong A, et al. Anti-inflammatory Activity of Methanolic Extracts From Ventilago Harmandiana Pierre. J Ethnopharmacol. 2004;91(2-3):237-42. PubMed PMID: 15120445.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre. AU - Panthong,Ampai, AU - Kanjanapothi,Duangta, AU - Taesotikul,Tawat, AU - Phankummoon,Apithai, AU - Panthong,Kanda, AU - Reutrakul,Vichai, PY - 2003/03/27/received PY - 2003/11/13/revised PY - 2003/12/23/accepted PY - 2004/5/4/pubmed PY - 2004/8/7/medline PY - 2004/5/4/entrez SP - 237 EP - 42 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 91 IS - 2-3 N2 - Methanolic extracts from the heart wood, stem bark, and stem wood of Ventilago harmandiana Pierre (Family Rhamnaceae) were assessed for anti-inflammatory effects using both acute and chronic inflammatory models. Analgesic and antipyretic activities of the extracts were also evaluated. It was found that all extracts possessed strong inhibitory effects on the acute phase of inflammation as seen in ethyl phenylpropiolate (EPP)- and arachidonic acid (AA)-induced ear edema as well as in carrageenin-induced paw edema in rats. The extracts elicited only weak inhibitory activity on cotton pellet-induced granuloma formation, a subchronic inflammatory model. In the analgesic test, all extracts exerted pronounced inhibitory activity in acetic acid-induced writhing response but showed only weak effects in the tail-flick test. The extracts also showed excellent antipyretic activity on yeast-induced hyperthermia in rats. SN - 0378-8741 UR - https://www.unboundmedicine.com/medline/citation/15120445/Anti_inflammatory_activity_of_methanolic_extracts_from_Ventilago_harmandiana_Pierre_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0378874104000236 DB - PRIME DP - Unbound Medicine ER -