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Anti-inflammatory evaluation of Ionidium suffruticosam Ging. in rats.
J Ethnopharmacol. 2004 Apr; 91(2-3):367-70.JE

Abstract

The anti-inflammatory activity of Ionidium suffruticosam (Violaceae) methanol extract was evaluated on carrageenin, histamine and serotonin-induced rat hind paw oedema acute models. The extract at doses of 200 and 400 mg/kg has been found to possess significant anti-inflammatory activity on the tested experimental models. The extract at the dose level of 400 mg/kg exhibited maximum anti-inflammatory activity in all the animal models. In a chronic test, the extract (400 mg/kg) showed 42.78% reduction in granuloma weight. The effect produced by the extract was comparable to that of phenylbutazone, a proto type of a non-steroidal anti-inflammatory agent.

Authors+Show Affiliations

Boominathan R
Division of Pharmacognosy, Department of Pharmaceutical Technology, Faculty of Engineering & Technology, Jadavpur University, Calcutta 700 032, India.
Parimaladevi B
No affiliation info available
Mandal SC
No affiliation info available
Ghoshal SK
No affiliation info available

MeSH

Administration, OralAnimalsAnti-Inflammatory AgentsCarrageenanCotton FiberDose-Response Relationship, DrugEdemaGranuloma, Foreign-BodyHistamineMalePhytotherapyPlant ExtractsPlant StructuresRatsRats, WistarSerotoninViolaceae

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15120463

Citation

Boominathan, R, et al. "Anti-inflammatory Evaluation of Ionidium Suffruticosam Ging. in Rats." Journal of Ethnopharmacology, vol. 91, no. 2-3, 2004, pp. 367-70.
Boominathan R, Parimaladevi B, Mandal SC, et al. Anti-inflammatory evaluation of Ionidium suffruticosam Ging. in rats. J Ethnopharmacol. 2004;91(2-3):367-70.
Boominathan, R., Parimaladevi, B., Mandal, S. C., & Ghoshal, S. K. (2004). Anti-inflammatory evaluation of Ionidium suffruticosam Ging. in rats. Journal of Ethnopharmacology, 91(2-3), 367-70.
Boominathan R, et al. Anti-inflammatory Evaluation of Ionidium Suffruticosam Ging. in Rats. J Ethnopharmacol. 2004;91(2-3):367-70. PubMed PMID: 15120463.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anti-inflammatory evaluation of Ionidium suffruticosam Ging. in rats. AU - Boominathan,R, AU - Parimaladevi,B, AU - Mandal,S C, AU - Ghoshal,S K, PY - 2003/03/05/received PY - 2003/12/05/revised PY - 2003/12/23/accepted PY - 2004/5/4/pubmed PY - 2004/8/7/medline PY - 2004/5/4/entrez SP - 367 EP - 70 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 91 IS - 2-3 N2 - The anti-inflammatory activity of Ionidium suffruticosam (Violaceae) methanol extract was evaluated on carrageenin, histamine and serotonin-induced rat hind paw oedema acute models. The extract at doses of 200 and 400 mg/kg has been found to possess significant anti-inflammatory activity on the tested experimental models. The extract at the dose level of 400 mg/kg exhibited maximum anti-inflammatory activity in all the animal models. In a chronic test, the extract (400 mg/kg) showed 42.78% reduction in granuloma weight. The effect produced by the extract was comparable to that of phenylbutazone, a proto type of a non-steroidal anti-inflammatory agent. SN - 0378-8741 UR - https://www.unboundmedicine.com/medline/citation/15120463/Anti_inflammatory_evaluation_of_Ionidium_suffruticosam_Ging__in_rats_ DB - PRIME DP - Unbound Medicine ER -