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Rapid genome evolution revealed by comparative sequence analysis of orthologous regions from four triticeae genomes.
Plant Physiol 2004; 135(1):459-70PP

Abstract

Bread wheat (Triticum aestivum) is an allohexaploid species, consisting of three subgenomes (A, B, and D). To study the molecular evolution of these closely related genomes, we compared the sequence of a 307-kb physical contig covering the high molecular weight (HMW)-glutenin locus from the A genome of durum wheat (Triticum turgidum, AABB) with the orthologous regions from the B genome of the same wheat and the D genome of the diploid wheat Aegilops tauschii (Anderson et al., 2003; Kong et al., 2004). Although gene colinearity appears to be retained, four out of six genes including the two paralogous HMW-glutenin genes are disrupted in the orthologous region of the A genome. Mechanisms involved in gene disruption in the A genome include retroelement insertions, sequence deletions, and mutations causing in-frame stop codons in the coding sequences. Comparative sequence analysis also revealed that sequences in the colinear intergenic regions of these different genomes were generally not conserved. The rapid genome evolution in these regions is attributable mainly to the large number of retrotransposon insertions that occurred after the divergence of the three wheat genomes. Our comparative studies indicate that the B genome diverged prior to the separation of the A and D genomes. Furthermore, sequence comparison of two distinct types of allelic variations at the HMW-glutenin loci in the A genomes of different hexaploid wheat cultivars with the A genome locus of durum wheat indicates that hexaploid wheat may have more than one tetraploid ancestor.

Authors+Show Affiliations

United States Department of Agriculture-Agricultural Research Service, Western Regional Research Center, Albany, California 94710, USA. ygu@pw.usda.govNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

15122014

Citation

Gu, Yong Qiang, et al. "Rapid Genome Evolution Revealed By Comparative Sequence Analysis of Orthologous Regions From Four Triticeae Genomes." Plant Physiology, vol. 135, no. 1, 2004, pp. 459-70.
Gu YQ, Coleman-Derr D, Kong X, et al. Rapid genome evolution revealed by comparative sequence analysis of orthologous regions from four triticeae genomes. Plant Physiol. 2004;135(1):459-70.
Gu, Y. Q., Coleman-Derr, D., Kong, X., & Anderson, O. D. (2004). Rapid genome evolution revealed by comparative sequence analysis of orthologous regions from four triticeae genomes. Plant Physiology, 135(1), pp. 459-70.
Gu YQ, et al. Rapid Genome Evolution Revealed By Comparative Sequence Analysis of Orthologous Regions From Four Triticeae Genomes. Plant Physiol. 2004;135(1):459-70. PubMed PMID: 15122014.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rapid genome evolution revealed by comparative sequence analysis of orthologous regions from four triticeae genomes. AU - Gu,Yong Qiang, AU - Coleman-Derr,Devin, AU - Kong,Xiuying, AU - Anderson,Olin D, Y1 - 2004/04/30/ PY - 2004/5/4/pubmed PY - 2004/10/16/medline PY - 2004/5/4/entrez SP - 459 EP - 70 JF - Plant physiology JO - Plant Physiol. VL - 135 IS - 1 N2 - Bread wheat (Triticum aestivum) is an allohexaploid species, consisting of three subgenomes (A, B, and D). To study the molecular evolution of these closely related genomes, we compared the sequence of a 307-kb physical contig covering the high molecular weight (HMW)-glutenin locus from the A genome of durum wheat (Triticum turgidum, AABB) with the orthologous regions from the B genome of the same wheat and the D genome of the diploid wheat Aegilops tauschii (Anderson et al., 2003; Kong et al., 2004). Although gene colinearity appears to be retained, four out of six genes including the two paralogous HMW-glutenin genes are disrupted in the orthologous region of the A genome. Mechanisms involved in gene disruption in the A genome include retroelement insertions, sequence deletions, and mutations causing in-frame stop codons in the coding sequences. Comparative sequence analysis also revealed that sequences in the colinear intergenic regions of these different genomes were generally not conserved. The rapid genome evolution in these regions is attributable mainly to the large number of retrotransposon insertions that occurred after the divergence of the three wheat genomes. Our comparative studies indicate that the B genome diverged prior to the separation of the A and D genomes. Furthermore, sequence comparison of two distinct types of allelic variations at the HMW-glutenin loci in the A genomes of different hexaploid wheat cultivars with the A genome locus of durum wheat indicates that hexaploid wheat may have more than one tetraploid ancestor. SN - 0032-0889 UR - https://www.unboundmedicine.com/medline/citation/15122014/Rapid_genome_evolution_revealed_by_comparative_sequence_analysis_of_orthologous_regions_from_four_triticeae_genomes_ L2 - http://www.plantphysiol.org/cgi/pmidlookup?view=long&pmid=15122014 DB - PRIME DP - Unbound Medicine ER -