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Immunosuppressive auronol glycosides from Artocarpus tonkinensis.
Pharmazie. 2004 Apr; 59(4):297-300.P

Abstract

Activity-guided fractionation of the n-butanol extract from the leaves of Artocarpus tonkinensis led to the isolation of the auronol glycosides maesopsin 4-O-glucoside (1), as well as the new alphitonin-4-O-glucoside (2). These structures were identified on the basis of MS and NMR spectroscopic data. The lymphocyte stimulation test showed both compounds having immunosuppressive activity.

Authors+Show Affiliations

Thuy TT
Institute of Chemistry, National Center for Natural Science and Technology, Cau Giay, Hanoi, Vietnam.
Kamperdick C
No affiliation info available
Ninh PT
No affiliation info available
Lien TP
No affiliation info available
Thao TT
No affiliation info available
Sung TV
No affiliation info available

MeSH

ArtocarpusBenzofuransCatechinCyclosporineGlucosidesGlycosidesHumansImmunosuppressive AgentsIn Vitro TechniquesIndicators and ReagentsLymphocytesMagnetic Resonance SpectroscopyPlant ExtractsPlant LeavesSpectrometry, Mass, Electrospray Ionization

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15125577

Citation

Thuy, T T., et al. "Immunosuppressive Auronol Glycosides From Artocarpus Tonkinensis." Die Pharmazie, vol. 59, no. 4, 2004, pp. 297-300.
Thuy TT, Kamperdick C, Ninh PT, et al. Immunosuppressive auronol glycosides from Artocarpus tonkinensis. Pharmazie. 2004;59(4):297-300.
Thuy, T. T., Kamperdick, C., Ninh, P. T., Lien, T. P., Thao, T. T., & Sung, T. V. (2004). Immunosuppressive auronol glycosides from Artocarpus tonkinensis. Die Pharmazie, 59(4), 297-300.
Thuy TT, et al. Immunosuppressive Auronol Glycosides From Artocarpus Tonkinensis. Pharmazie. 2004;59(4):297-300. PubMed PMID: 15125577.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Immunosuppressive auronol glycosides from Artocarpus tonkinensis. AU - Thuy,T T, AU - Kamperdick,C, AU - Ninh,P T, AU - Lien,T P, AU - Thao,T T P, AU - Sung,T V, PY - 2004/5/6/pubmed PY - 2004/6/4/medline PY - 2004/5/6/entrez SP - 297 EP - 300 JF - Die Pharmazie JO - Pharmazie VL - 59 IS - 4 N2 - Activity-guided fractionation of the n-butanol extract from the leaves of Artocarpus tonkinensis led to the isolation of the auronol glycosides maesopsin 4-O-glucoside (1), as well as the new alphitonin-4-O-glucoside (2). These structures were identified on the basis of MS and NMR spectroscopic data. The lymphocyte stimulation test showed both compounds having immunosuppressive activity. SN - 0031-7144 UR - https://www.unboundmedicine.com/medline/citation/15125577/Immunosuppressive_auronol_glycosides_from_Artocarpus_tonkinensis_ DB - PRIME DP - Unbound Medicine ER -