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[Isolation and structure identification of chemical constituents from the seeds of Descurainia sophia (L.) Webb ex Prantl].
Yao Xue Xue Bao. 2004 Jan; 39(1):46-51.YX

Abstract

AIM

To isolate and determine the structures of chemical constituents from the seeds of Descurainia sophia (L.) Webb ex Prantl.

METHODS

The chemical constituents were extracted from the seeds of Descurainia sophia (L.) Webb ex Prantl with 75% ethanol and purified by polyamide, silica gel, RP-C18 and Sephadex LH-20 on column chromatography. Chemical methods and spectroscopic methods, such as 1H and 13CNMR, HSQC, HMBC and TOCSY spectra were used for the structural identification.

RESULTS

Fifteen compounds were obtained. Twelve of them were identified as quercetin-3-O-beta-D-glucopyranosyl-7-O-beta-gentiobioside (I), kaempferol-3-O-beta-D-glucopyranosyl-7-O-beta-gentiobioside (II), isorhamnetin-3-O-beta-D-glucopyranosyl-7-O-beta-gentiobioside (III), quercetin-7-O-beta-gentiobioside (IV), kaempferol-7-O-beta-gentiobioside (V), isorhamnetin-7-O-beta-gentiobioside (VI), quercetin-3,7-di-O-beta-D-glucopyranoside (VII), kaempferol-3, 7-di-O-beta-D-glucopyranoside (VIII), isorhamnetin-3, 7-di-O-beta-D-glucopyranoside (IX), kaempferol-3-O-beta-D-glucopyranosyl-7-O-[(2-O-trans-sinnapoyl)-beta-D- glucopyranosyl(1-->6)]-beta-D-glucopyranoside) (X), sinapic acid ethyl ester (XI) and 3, 4, 5-trimethoxyl-cinnamic acid (XII).

CONCLUSION

Compounds X and VI are new compounds. IV, V, VII, VIII and IX were isolated from Cruciferae family for the first time. I, II, III were obtained from Descurania genus and XI, XII from D. sophia for the first time.

Authors+Show Affiliations

Beijing University of Traditional Chinese Medicine, Beijing 100102, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

15127581

Citation

Wang, Ai-qin, et al. "[Isolation and Structure Identification of Chemical Constituents From the Seeds of Descurainia Sophia (L.) Webb Ex Prantl]." Yao Xue Xue Bao = Acta Pharmaceutica Sinica, vol. 39, no. 1, 2004, pp. 46-51.
Wang AQ, Wang XK, Li JL, et al. [Isolation and structure identification of chemical constituents from the seeds of Descurainia sophia (L.) Webb ex Prantl]. Yao Xue Xue Bao. 2004;39(1):46-51.
Wang, A. Q., Wang, X. K., Li, J. L., & Cui, X. Y. (2004). [Isolation and structure identification of chemical constituents from the seeds of Descurainia sophia (L.) Webb ex Prantl]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica, 39(1), 46-51.
Wang AQ, et al. [Isolation and Structure Identification of Chemical Constituents From the Seeds of Descurainia Sophia (L.) Webb Ex Prantl]. Yao Xue Xue Bao. 2004;39(1):46-51. PubMed PMID: 15127581.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Isolation and structure identification of chemical constituents from the seeds of Descurainia sophia (L.) Webb ex Prantl]. AU - Wang,Ai-qin, AU - Wang,Xiu-kun, AU - Li,Jun-lin, AU - Cui,Xiang-yu, PY - 2004/5/7/pubmed PY - 2004/8/3/medline PY - 2004/5/7/entrez SP - 46 EP - 51 JF - Yao xue xue bao = Acta pharmaceutica Sinica JO - Yao Xue Xue Bao VL - 39 IS - 1 N2 - AIM: To isolate and determine the structures of chemical constituents from the seeds of Descurainia sophia (L.) Webb ex Prantl. METHODS: The chemical constituents were extracted from the seeds of Descurainia sophia (L.) Webb ex Prantl with 75% ethanol and purified by polyamide, silica gel, RP-C18 and Sephadex LH-20 on column chromatography. Chemical methods and spectroscopic methods, such as 1H and 13CNMR, HSQC, HMBC and TOCSY spectra were used for the structural identification. RESULTS: Fifteen compounds were obtained. Twelve of them were identified as quercetin-3-O-beta-D-glucopyranosyl-7-O-beta-gentiobioside (I), kaempferol-3-O-beta-D-glucopyranosyl-7-O-beta-gentiobioside (II), isorhamnetin-3-O-beta-D-glucopyranosyl-7-O-beta-gentiobioside (III), quercetin-7-O-beta-gentiobioside (IV), kaempferol-7-O-beta-gentiobioside (V), isorhamnetin-7-O-beta-gentiobioside (VI), quercetin-3,7-di-O-beta-D-glucopyranoside (VII), kaempferol-3, 7-di-O-beta-D-glucopyranoside (VIII), isorhamnetin-3, 7-di-O-beta-D-glucopyranoside (IX), kaempferol-3-O-beta-D-glucopyranosyl-7-O-[(2-O-trans-sinnapoyl)-beta-D- glucopyranosyl(1-->6)]-beta-D-glucopyranoside) (X), sinapic acid ethyl ester (XI) and 3, 4, 5-trimethoxyl-cinnamic acid (XII). CONCLUSION: Compounds X and VI are new compounds. IV, V, VII, VIII and IX were isolated from Cruciferae family for the first time. I, II, III were obtained from Descurania genus and XI, XII from D. sophia for the first time. SN - 0513-4870 UR - https://www.unboundmedicine.com/medline/citation/15127581/[Isolation_and_structure_identification_of_chemical_constituents_from_the_seeds_of_Descurainia_sophia__L___Webb_ex_Prantl]_ DB - PRIME DP - Unbound Medicine ER -
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