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Role of vitamins in the risk, prevention, and treatment of breast cancer.
Curr Opin Obstet Gynecol 2004; 16(1):19-25CO

Abstract

PURPOSE OF REVIEW

This article presents an overview of the role of vitamins in the risk, prevention, and treatment of breast cancer, with emphasis on current evidence from English-language articles published since 1 August 2002 and indexed in MEDLINE.

RECENT FINDINGS

Findings from epidemiologic studies that have evaluated vitamin A and carotenoids in relation to breast cancer risk have been inconclusive. The available data, especially from prospective studies, do not support an association between vitamins E and C and risk of breast cancer. Recent studies suggest that folate plays an important role in the prevention of breast cancer, particularly among women consuming alcohol. Limited data also support a potential role of vitamin D in the prevention of breast cancer.

SUMMARY

High intake of folate or adequate circulating levels of folate may reduce the risk of breast cancer. Adequate folate levels may be particularly important for women who are at higher risk of breast cancer because of high alcohol consumption. The inverse association between vitamin D and risk of breast cancer needs to be evaluated in more studies.

Authors+Show Affiliations

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA. shumin.zhang@channing.harvard.edu

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15128003

Citation

Zhang, Shumin M.. "Role of Vitamins in the Risk, Prevention, and Treatment of Breast Cancer." Current Opinion in Obstetrics & Gynecology, vol. 16, no. 1, 2004, pp. 19-25.
Zhang SM. Role of vitamins in the risk, prevention, and treatment of breast cancer. Curr Opin Obstet Gynecol. 2004;16(1):19-25.
Zhang, S. M. (2004). Role of vitamins in the risk, prevention, and treatment of breast cancer. Current Opinion in Obstetrics & Gynecology, 16(1), pp. 19-25.
Zhang SM. Role of Vitamins in the Risk, Prevention, and Treatment of Breast Cancer. Curr Opin Obstet Gynecol. 2004;16(1):19-25. PubMed PMID: 15128003.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Role of vitamins in the risk, prevention, and treatment of breast cancer. A1 - Zhang,Shumin M, PY - 2004/5/7/pubmed PY - 2004/6/4/medline PY - 2004/5/7/entrez SP - 19 EP - 25 JF - Current opinion in obstetrics & gynecology JO - Curr. Opin. Obstet. Gynecol. VL - 16 IS - 1 N2 - PURPOSE OF REVIEW: This article presents an overview of the role of vitamins in the risk, prevention, and treatment of breast cancer, with emphasis on current evidence from English-language articles published since 1 August 2002 and indexed in MEDLINE. RECENT FINDINGS: Findings from epidemiologic studies that have evaluated vitamin A and carotenoids in relation to breast cancer risk have been inconclusive. The available data, especially from prospective studies, do not support an association between vitamins E and C and risk of breast cancer. Recent studies suggest that folate plays an important role in the prevention of breast cancer, particularly among women consuming alcohol. Limited data also support a potential role of vitamin D in the prevention of breast cancer. SUMMARY: High intake of folate or adequate circulating levels of folate may reduce the risk of breast cancer. Adequate folate levels may be particularly important for women who are at higher risk of breast cancer because of high alcohol consumption. The inverse association between vitamin D and risk of breast cancer needs to be evaluated in more studies. SN - 1040-872X UR - https://www.unboundmedicine.com/medline/citation/15128003/Role_of_vitamins_in_the_risk_prevention_and_treatment_of_breast_cancer_ L2 - http://dx.doi.org/10.1097/00001703-200402000-00005 DB - PRIME DP - Unbound Medicine ER -