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Visual axis opacification after AcrySof intraocular lens implantation in children.
J Cataract Refract Surg. 2004 May; 30(5):1073-81.JC

Abstract

PURPOSE

To evaluate visual axis opacification after AcrySof intraocular lens (IOL) (Alcon) implantation in pediatric eyes.

SETTING

Iladevi Cataract and IOL Research Centre, Ahmedabad, India.

METHODS

This prospective study evaluated 103 consecutive eyes of 72 children with congenital cataract. Two groups were formed based on age at surgery: Group 1, younger than 2 years, and Group 2, older than 2 years. All eyes in Group 1 (n = 37) had primary posterior continuous curvilinear capsulorhexis (PCCC) with anterior vitrectomy. In Group 2 (n = 66), management of the posterior capsule was assigned randomly to no PCCC (Group 2A, n = 37) or PCCC (Group 2B, n = 29). The PCCC group was further randomized into 2 subgroups: no vitrectomy (Group 2BN, n = 14) or vitrectomy (Group 2BV, n = 15). The primary outcome measures were visual axis opacification and the resulting need for a secondary procedure. Statistical analysis was performed using SPSS for Windows (version 11.0.1).

RESULTS

The mean age of the patients was 5.2 years +/- 5.0 (SD) (range 0.2 to 16.0 years) and the mean follow-up, 2.3 +/- 0.9 years (range 1.0 to 4.0 years). Overall, 41 eyes (39.8%) developed visual axis opacification and 14 (13.6%) required secondary intervention. In Group 1, 4 eyes (10.8%) developed visual axis opacification and 3 (8.1%) had a secondary pars plana vitrectomy. In Group 2A, 31 eyes (83.8%) developed posterior capsule opacification (PCO) and 10 eyes (27.7%) had secondary intervention. Children 8 years or younger at the time of surgery developed significantly greater PCO than older children (P =.01). Five eyes (37.5%) in Group 2BN had opacification of the anterior vitreous face, 1 of which required a secondary procedure. One eye (6.7%) in Group 2BV had visual axis opacification that did not require a secondary procedure.

CONCLUSIONS

AcrySof IOL implantation with appropriate management of the posterior capsule maintained a clear visual axis in 60.2% of eyes. Of the 39.8% of eyes with visual axis opacification, 13.6% had visually significant opacification and required a secondary procedure.

Authors+Show Affiliations

Iladevi Cataract and IOL Research Centre, Ahmedabad, India. shailad1@sancharnet.inNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

15130646

Citation

Vasavada, Abhay R., et al. "Visual Axis Opacification After AcrySof Intraocular Lens Implantation in Children." Journal of Cataract and Refractive Surgery, vol. 30, no. 5, 2004, pp. 1073-81.
Vasavada AR, Trivedi RH, Nath VC. Visual axis opacification after AcrySof intraocular lens implantation in children. J Cataract Refract Surg. 2004;30(5):1073-81.
Vasavada, A. R., Trivedi, R. H., & Nath, V. C. (2004). Visual axis opacification after AcrySof intraocular lens implantation in children. Journal of Cataract and Refractive Surgery, 30(5), 1073-81.
Vasavada AR, Trivedi RH, Nath VC. Visual Axis Opacification After AcrySof Intraocular Lens Implantation in Children. J Cataract Refract Surg. 2004;30(5):1073-81. PubMed PMID: 15130646.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Visual axis opacification after AcrySof intraocular lens implantation in children. AU - Vasavada,Abhay R, AU - Trivedi,Rupal H, AU - Nath,Vandana C, PY - 2003/08/06/accepted PY - 2004/5/8/pubmed PY - 2004/6/24/medline PY - 2004/5/8/entrez SP - 1073 EP - 81 JF - Journal of cataract and refractive surgery JO - J Cataract Refract Surg VL - 30 IS - 5 N2 - PURPOSE: To evaluate visual axis opacification after AcrySof intraocular lens (IOL) (Alcon) implantation in pediatric eyes. SETTING: Iladevi Cataract and IOL Research Centre, Ahmedabad, India. METHODS: This prospective study evaluated 103 consecutive eyes of 72 children with congenital cataract. Two groups were formed based on age at surgery: Group 1, younger than 2 years, and Group 2, older than 2 years. All eyes in Group 1 (n = 37) had primary posterior continuous curvilinear capsulorhexis (PCCC) with anterior vitrectomy. In Group 2 (n = 66), management of the posterior capsule was assigned randomly to no PCCC (Group 2A, n = 37) or PCCC (Group 2B, n = 29). The PCCC group was further randomized into 2 subgroups: no vitrectomy (Group 2BN, n = 14) or vitrectomy (Group 2BV, n = 15). The primary outcome measures were visual axis opacification and the resulting need for a secondary procedure. Statistical analysis was performed using SPSS for Windows (version 11.0.1). RESULTS: The mean age of the patients was 5.2 years +/- 5.0 (SD) (range 0.2 to 16.0 years) and the mean follow-up, 2.3 +/- 0.9 years (range 1.0 to 4.0 years). Overall, 41 eyes (39.8%) developed visual axis opacification and 14 (13.6%) required secondary intervention. In Group 1, 4 eyes (10.8%) developed visual axis opacification and 3 (8.1%) had a secondary pars plana vitrectomy. In Group 2A, 31 eyes (83.8%) developed posterior capsule opacification (PCO) and 10 eyes (27.7%) had secondary intervention. Children 8 years or younger at the time of surgery developed significantly greater PCO than older children (P =.01). Five eyes (37.5%) in Group 2BN had opacification of the anterior vitreous face, 1 of which required a secondary procedure. One eye (6.7%) in Group 2BV had visual axis opacification that did not require a secondary procedure. CONCLUSIONS: AcrySof IOL implantation with appropriate management of the posterior capsule maintained a clear visual axis in 60.2% of eyes. Of the 39.8% of eyes with visual axis opacification, 13.6% had visually significant opacification and required a secondary procedure. SN - 0886-3350 UR - https://www.unboundmedicine.com/medline/citation/15130646/Visual_axis_opacification_after_AcrySof_intraocular_lens_implantation_in_children_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0886335003008289 DB - PRIME DP - Unbound Medicine ER -