Tags

Type your tag names separated by a space and hit enter

Toxicological considerations of Kampo medicines in clinical use.
Toxicology. 2004 May 20; 198(1-3):221-8.T

Abstract

Kampo (Japanese herbal) medicines, produced by combining multiple crude drugs, almost all of plant origin but with some of animal or mineral origin, contain great many substances. Since Kampo medicine results from the combination of many substances, their effect is a combination of the various interactions of the constituent substances. It has been demonstrated that several potential side effects such as allergic reactions, diarrhea and vomiting may be experienced when administering Kampo medicine. In addition, it has been reported that Kampo medicine may have antagonistic or synergistic interactions with western drugs or with some foods such as grapefruit juice. Among the 210 medicinal prescriptions used in present-day Japan, the clinical uses and the acute, chronic and mutagenic toxicity of some Kampo medicines are described. Studies of some potential interaction between Kampo medicines and western drugs are also considered.

Authors+Show Affiliations

Center for Environment, Health and Field Sciences, Chiba University, Kashiwanoha 6-2-1, Kashiwa 277-0882, Japan. ikegami@faculty.chiba.u.jpNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15138045

Citation

Ikegami, Fumio, et al. "Toxicological Considerations of Kampo Medicines in Clinical Use." Toxicology, vol. 198, no. 1-3, 2004, pp. 221-8.
Ikegami F, Fujii Y, Satoh T. Toxicological considerations of Kampo medicines in clinical use. Toxicology. 2004;198(1-3):221-8.
Ikegami, F., Fujii, Y., & Satoh, T. (2004). Toxicological considerations of Kampo medicines in clinical use. Toxicology, 198(1-3), 221-8.
Ikegami F, Fujii Y, Satoh T. Toxicological Considerations of Kampo Medicines in Clinical Use. Toxicology. 2004 May 20;198(1-3):221-8. PubMed PMID: 15138045.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Toxicological considerations of Kampo medicines in clinical use. AU - Ikegami,Fumio, AU - Fujii,Yuichi, AU - Satoh,Tetsuo, PY - 2004/5/13/pubmed PY - 2004/6/18/medline PY - 2004/5/13/entrez SP - 221 EP - 8 JF - Toxicology JO - Toxicology VL - 198 IS - 1-3 N2 - Kampo (Japanese herbal) medicines, produced by combining multiple crude drugs, almost all of plant origin but with some of animal or mineral origin, contain great many substances. Since Kampo medicine results from the combination of many substances, their effect is a combination of the various interactions of the constituent substances. It has been demonstrated that several potential side effects such as allergic reactions, diarrhea and vomiting may be experienced when administering Kampo medicine. In addition, it has been reported that Kampo medicine may have antagonistic or synergistic interactions with western drugs or with some foods such as grapefruit juice. Among the 210 medicinal prescriptions used in present-day Japan, the clinical uses and the acute, chronic and mutagenic toxicity of some Kampo medicines are described. Studies of some potential interaction between Kampo medicines and western drugs are also considered. SN - 0300-483X UR - https://www.unboundmedicine.com/medline/citation/15138045/Toxicological_considerations_of_Kampo_medicines_in_clinical_use_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0300483X04000940 DB - PRIME DP - Unbound Medicine ER -