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Outbreak of varicella among vaccinated children--Michigan, 2003.
MMWR Morb Mortal Wkly Rep. 2004 May 14; 53(18):389-92.MM

Abstract

On November 18, 2003, the Oakland County Health Division alerted the Michigan Department of Community Health (MDCH) to a varicella (chicken pox) outbreak in a kindergarten-third grade elementary school. On December 11, MDCH and Oakland County public health epidemiologists, with the technical assistance of CDC, conducted a retrospective cohort study to describe the outbreak, determine varicella vaccine effectiveness (VE), and examine risk factors for breakthrough disease (i.e., varicella occurring >42 days after vaccination). This report summarizes the results of that study, which indicated that 1) transmission of varicella was sustained at the school for nearly 1 month despite high vaccination coverage, 2) vaccinated patients had substantially milder disease (<50 lesions), and 3) a period of > or =4 years since vaccination was a risk factor for breakthrough disease. These findings highlight the importance of case-based reporting of varicella and the exclusion of patients from school until all lesions crust or fade away. Information about recognizing vaccinated patients with mild cases should be disseminated to health-care providers, school administrators, and parents.

Authors

Centers for Disease Control and Prevention (CDC)
No affiliation info available

MeSH

ChickenpoxChickenpox VaccineChildDisease OutbreaksHumansMichiganSchoolsVaccination

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15138400

Citation

Centers for Disease Control and Prevention (CDC). "Outbreak of Varicella Among Vaccinated children--Michigan, 2003." MMWR. Morbidity and Mortality Weekly Report, vol. 53, no. 18, 2004, pp. 389-92.
Centers for Disease Control and Prevention (CDC). Outbreak of varicella among vaccinated children--Michigan, 2003. MMWR Morb Mortal Wkly Rep. 2004;53(18):389-92.
Centers for Disease Control and Prevention (CDC). (2004). Outbreak of varicella among vaccinated children--Michigan, 2003. MMWR. Morbidity and Mortality Weekly Report, 53(18), 389-92.
Centers for Disease Control and Prevention (CDC). Outbreak of Varicella Among Vaccinated children--Michigan, 2003. MMWR Morb Mortal Wkly Rep. 2004 May 14;53(18):389-92. PubMed PMID: 15138400.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outbreak of varicella among vaccinated children--Michigan, 2003. A1 - ,, PY - 2004/5/13/pubmed PY - 2004/5/18/medline PY - 2004/5/13/entrez SP - 389 EP - 92 JF - MMWR. Morbidity and mortality weekly report JO - MMWR Morb Mortal Wkly Rep VL - 53 IS - 18 N2 - On November 18, 2003, the Oakland County Health Division alerted the Michigan Department of Community Health (MDCH) to a varicella (chicken pox) outbreak in a kindergarten-third grade elementary school. On December 11, MDCH and Oakland County public health epidemiologists, with the technical assistance of CDC, conducted a retrospective cohort study to describe the outbreak, determine varicella vaccine effectiveness (VE), and examine risk factors for breakthrough disease (i.e., varicella occurring >42 days after vaccination). This report summarizes the results of that study, which indicated that 1) transmission of varicella was sustained at the school for nearly 1 month despite high vaccination coverage, 2) vaccinated patients had substantially milder disease (<50 lesions), and 3) a period of > or =4 years since vaccination was a risk factor for breakthrough disease. These findings highlight the importance of case-based reporting of varicella and the exclusion of patients from school until all lesions crust or fade away. Information about recognizing vaccinated patients with mild cases should be disseminated to health-care providers, school administrators, and parents. SN - 1545-861X UR - https://www.unboundmedicine.com/medline/citation/15138400/Outbreak_of_varicella_among_vaccinated_children__Michigan_2003_ DB - PRIME DP - Unbound Medicine ER -