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Monochromatic excimer light (308 nm) in patch-stage IA mycosis fungoides.
J Am Acad Dermatol. 2004 Jun; 50(6):943-5.JA

Abstract

Recently, numerous studies have been reported concerning the treatment of early-stage mycosis fungoides (MF) with narrowband (311-nm) UVB, claiming a beneficial response. We have used for the first time a 308-nm monochromatic excimer light, a new kind of xenon-chloride lamp, in the treatment of patch stage IA MF. We treated 7 patch lesions in 4 patients with unequivocal clinicopathologic diagnosis of MF. All lesions achieved clinical and histologic complete remission. The number of weekly sessions varied from 4 to 11 (mean 6.5; median 5.5). The total UVB 308-nm irradiation dose ranged from 5 to 9.3 J/cm(2) (mean 7.1 J/cm(2); median 7 J/cm(2)). All lesions remained in stable complete remission after a follow-up of 3 to 28 months. No remarkable side effects were reported. Our preliminary results suggest that monochromatic excimer light phototherapy is a possibly very useful treatment modality in patch stage IA MF.

Authors+Show Affiliations

Department of Dermatological Sciences, University of Florence Medical School, Florence, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15153899

Citation

Mori, Moira, et al. "Monochromatic Excimer Light (308 Nm) in Patch-stage IA Mycosis Fungoides." Journal of the American Academy of Dermatology, vol. 50, no. 6, 2004, pp. 943-5.
Mori M, Campolmi P, Mavilia L, et al. Monochromatic excimer light (308 nm) in patch-stage IA mycosis fungoides. J Am Acad Dermatol. 2004;50(6):943-5.
Mori, M., Campolmi, P., Mavilia, L., Rossi, R., Cappugi, P., & Pimpinelli, N. (2004). Monochromatic excimer light (308 nm) in patch-stage IA mycosis fungoides. Journal of the American Academy of Dermatology, 50(6), 943-5.
Mori M, et al. Monochromatic Excimer Light (308 Nm) in Patch-stage IA Mycosis Fungoides. J Am Acad Dermatol. 2004;50(6):943-5. PubMed PMID: 15153899.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Monochromatic excimer light (308 nm) in patch-stage IA mycosis fungoides. AU - Mori,Moira, AU - Campolmi,Piero, AU - Mavilia,Luciano, AU - Rossi,Riccardo, AU - Cappugi,Pietro, AU - Pimpinelli,Nicola, PY - 2004/5/22/pubmed PY - 2004/7/15/medline PY - 2004/5/22/entrez SP - 943 EP - 5 JF - Journal of the American Academy of Dermatology JO - J. Am. Acad. Dermatol. VL - 50 IS - 6 N2 - Recently, numerous studies have been reported concerning the treatment of early-stage mycosis fungoides (MF) with narrowband (311-nm) UVB, claiming a beneficial response. We have used for the first time a 308-nm monochromatic excimer light, a new kind of xenon-chloride lamp, in the treatment of patch stage IA MF. We treated 7 patch lesions in 4 patients with unequivocal clinicopathologic diagnosis of MF. All lesions achieved clinical and histologic complete remission. The number of weekly sessions varied from 4 to 11 (mean 6.5; median 5.5). The total UVB 308-nm irradiation dose ranged from 5 to 9.3 J/cm(2) (mean 7.1 J/cm(2); median 7 J/cm(2)). All lesions remained in stable complete remission after a follow-up of 3 to 28 months. No remarkable side effects were reported. Our preliminary results suggest that monochromatic excimer light phototherapy is a possibly very useful treatment modality in patch stage IA MF. SN - 0190-9622 UR - https://www.unboundmedicine.com/medline/citation/15153899/Monochromatic_excimer_light__308_nm__in_patch_stage_IA_mycosis_fungoides_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0190962204005274 DB - PRIME DP - Unbound Medicine ER -