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5-methylcoumaranones from Mutisia friesiana and their bioactivity.
J Nat Prod. 2004 May; 67(5):778-82.JN

Abstract

In addition to the known mutisicoumaranones A (1) and B (2), the methanolic extract of the aerial parts of the shrub Mutisia friesiana afforded two new 5-methylcoumaranones, mutisicoumaranones C (3) and D (4). Their structures were elucidated by spectroscopic methods. (13)C NMR data for mutisicoumaranones A and B are reported for the first time. All compounds showed antifungal activity against the phytopathogenic fungus Cladosporium cucumerinum and bactericidal activity against Staphylococcus aureus. The presence of 5-methylcoumaranones A-D is biosynthetically related to 5-methylcoumarins and phenolic derivatives previously isolated from M. friesiana.

Authors+Show Affiliations

Viturro CI
Facultad de Ingeniería, Universidad Nacional de Jujuy, Gorriti 237, 4600 S. S. de Jujuy, Jujuy, Argentina.
de la Fuente JR
No affiliation info available
Maier MS
No affiliation info available

MeSH

Antifungal AgentsArgentinaAsteraceaeBenzofuransCladosporiumMicrobial Sensitivity TestsMolecular StructureNuclear Magnetic Resonance, BiomolecularPlants, MedicinalStaphylococcus aureus

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15165137

Citation

Viturro, Carmen I., et al. "5-methylcoumaranones From Mutisia Friesiana and Their Bioactivity." Journal of Natural Products, vol. 67, no. 5, 2004, pp. 778-82.
Viturro CI, de la Fuente JR, Maier MS. 5-methylcoumaranones from Mutisia friesiana and their bioactivity. J Nat Prod. 2004;67(5):778-82.
Viturro, C. I., de la Fuente, J. R., & Maier, M. S. (2004). 5-methylcoumaranones from Mutisia friesiana and their bioactivity. Journal of Natural Products, 67(5), 778-82.
Viturro CI, de la Fuente JR, Maier MS. 5-methylcoumaranones From Mutisia Friesiana and Their Bioactivity. J Nat Prod. 2004;67(5):778-82. PubMed PMID: 15165137.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - 5-methylcoumaranones from Mutisia friesiana and their bioactivity. AU - Viturro,Carmen I, AU - de la Fuente,Juana R, AU - Maier,Marta S, PY - 2004/5/29/pubmed PY - 2004/6/25/medline PY - 2004/5/29/entrez SP - 778 EP - 82 JF - Journal of natural products JO - J Nat Prod VL - 67 IS - 5 N2 - In addition to the known mutisicoumaranones A (1) and B (2), the methanolic extract of the aerial parts of the shrub Mutisia friesiana afforded two new 5-methylcoumaranones, mutisicoumaranones C (3) and D (4). Their structures were elucidated by spectroscopic methods. (13)C NMR data for mutisicoumaranones A and B are reported for the first time. All compounds showed antifungal activity against the phytopathogenic fungus Cladosporium cucumerinum and bactericidal activity against Staphylococcus aureus. The presence of 5-methylcoumaranones A-D is biosynthetically related to 5-methylcoumarins and phenolic derivatives previously isolated from M. friesiana. SN - 0163-3864 UR - https://www.unboundmedicine.com/medline/citation/15165137/5_methylcoumaranones_from_Mutisia_friesiana_and_their_bioactivity_ DB - PRIME DP - Unbound Medicine ER -