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Resting metabolic rate in severely obese diabetic and nondiabetic subjects.
Obes Res. 2004 May; 12(5):840-5.OR

Abstract

OBJECTIVES

To compare the resting metabolic rate (RMR) between diabetic and nondiabetic obese subjects and to develop a predictive equation of RMR for these subjects.

RESEARCH METHODS AND PROCEDURES

Obese adults (1088; mean age = 44.9 +/- 12.7 years) with BMI > or = 35 kg/m2 (mean BMI = 46.4 +/- 8.4 kg/m2) were recruited. One hundred forty-two subjects (61 men, 81 women) were diagnosed with type 2 diabetes (DM), giving the prevalence of DM in this clinic population as 13.7%. RMR was measured by indirect calorimetry, and several multivariate linear regression models were performed using age, gender, weight, height, BMI, fat mass, fat mass percentage, and fat-free mass as independent variables.

RESULTS

The severely obese patients with DM had consistently higher RMR after adjustment for all other variables. The best predictive equation for the severely obese was RMR = 71.767 - 2.337 x age + 257.293 x gender (women = 0 and men = 1) + 9.996 x weight (in kilograms) + 4.132 x height (in centimeters) + 145.959 x DM (nondiabetic = 0 and diabetic = 1). The age, weight, and height-adjusted least square means of RMR between diabetic and nondiabetic groups were significantly different in both genders.

DISCUSSION

Severely obese patients with type 2 diabetes had higher RMR than those without diabetes. The RMR of severely obese subjects was best predicted by an equation using age, gender, weight, height, and DM as variables.

Authors+Show Affiliations

Metabolism and Obesity Services, Department of Endocrinology, Royal Prince Alfred Hospital, New South Wales, Australia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15166305

Citation

Huang, Kuo-Chin, et al. "Resting Metabolic Rate in Severely Obese Diabetic and Nondiabetic Subjects." Obesity Research, vol. 12, no. 5, 2004, pp. 840-5.
Huang KC, Kormas N, Steinbeck K, et al. Resting metabolic rate in severely obese diabetic and nondiabetic subjects. Obes Res. 2004;12(5):840-5.
Huang, K. C., Kormas, N., Steinbeck, K., Loughnan, G., & Caterson, I. D. (2004). Resting metabolic rate in severely obese diabetic and nondiabetic subjects. Obesity Research, 12(5), 840-5.
Huang KC, et al. Resting Metabolic Rate in Severely Obese Diabetic and Nondiabetic Subjects. Obes Res. 2004;12(5):840-5. PubMed PMID: 15166305.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Resting metabolic rate in severely obese diabetic and nondiabetic subjects. AU - Huang,Kuo-Chin, AU - Kormas,Nic, AU - Steinbeck,Katharine, AU - Loughnan,Georgina, AU - Caterson,Ian D, PY - 2004/5/29/pubmed PY - 2004/10/7/medline PY - 2004/5/29/entrez SP - 840 EP - 5 JF - Obesity research JO - Obes Res VL - 12 IS - 5 N2 - OBJECTIVES: To compare the resting metabolic rate (RMR) between diabetic and nondiabetic obese subjects and to develop a predictive equation of RMR for these subjects. RESEARCH METHODS AND PROCEDURES: Obese adults (1088; mean age = 44.9 +/- 12.7 years) with BMI > or = 35 kg/m2 (mean BMI = 46.4 +/- 8.4 kg/m2) were recruited. One hundred forty-two subjects (61 men, 81 women) were diagnosed with type 2 diabetes (DM), giving the prevalence of DM in this clinic population as 13.7%. RMR was measured by indirect calorimetry, and several multivariate linear regression models were performed using age, gender, weight, height, BMI, fat mass, fat mass percentage, and fat-free mass as independent variables. RESULTS: The severely obese patients with DM had consistently higher RMR after adjustment for all other variables. The best predictive equation for the severely obese was RMR = 71.767 - 2.337 x age + 257.293 x gender (women = 0 and men = 1) + 9.996 x weight (in kilograms) + 4.132 x height (in centimeters) + 145.959 x DM (nondiabetic = 0 and diabetic = 1). The age, weight, and height-adjusted least square means of RMR between diabetic and nondiabetic groups were significantly different in both genders. DISCUSSION: Severely obese patients with type 2 diabetes had higher RMR than those without diabetes. The RMR of severely obese subjects was best predicted by an equation using age, gender, weight, height, and DM as variables. SN - 1071-7323 UR - https://www.unboundmedicine.com/medline/citation/15166305/Resting_metabolic_rate_in_severely_obese_diabetic_and_nondiabetic_subjects_ L2 - https://doi.org/10.1038/oby.2004.101 DB - PRIME DP - Unbound Medicine ER -