Combination of ziprasidone and clozapine in treatment-resistant schizophrenia.Hum Psychopharmacol. 2004 Jun; 19(4):271-3.HP
Abstract
In cases of treatment-resistant schizophrenia the combined application of antipsychotic drugs often becomes necessary. Clozapine has been combined successfully with other atypical antipsychotic drugs such as risperidone or amisulpride in the past. We report the difficult treatment of a 28-year-old schizophrenic woman. Psychotic symptoms were found resistant to monotherapy with clozapine or ziprasidone. In contrast, combined application led to a marked improvement in both positive and negative symptoms of schizophrenia along with a decrease of side effects.The reported combination is a promising option in cases of treatment-resistant schizophrenia and should be further evaluated in prospective studies.
Links
MeSH
Pub Type(s)
Case Reports
Journal Article
Language
eng
PubMed ID
15181656
Citation
Zink, M, et al. "Combination of Ziprasidone and Clozapine in Treatment-resistant Schizophrenia." Human Psychopharmacology, vol. 19, no. 4, 2004, pp. 271-3.
Zink M, Mase E, Dressing H. Combination of ziprasidone and clozapine in treatment-resistant schizophrenia. Hum Psychopharmacol. 2004;19(4):271-3.
Zink, M., Mase, E., & Dressing, H. (2004). Combination of ziprasidone and clozapine in treatment-resistant schizophrenia. Human Psychopharmacology, 19(4), 271-3.
Zink M, Mase E, Dressing H. Combination of Ziprasidone and Clozapine in Treatment-resistant Schizophrenia. Hum Psychopharmacol. 2004;19(4):271-3. PubMed PMID: 15181656.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Combination of ziprasidone and clozapine in treatment-resistant schizophrenia.
AU - Zink,M,
AU - Mase,E,
AU - Dressing,H,
PY - 2004/6/8/pubmed
PY - 2004/12/16/medline
PY - 2004/6/8/entrez
SP - 271
EP - 3
JF - Human psychopharmacology
JO - Hum Psychopharmacol
VL - 19
IS - 4
N2 - In cases of treatment-resistant schizophrenia the combined application of antipsychotic drugs often becomes necessary. Clozapine has been combined successfully with other atypical antipsychotic drugs such as risperidone or amisulpride in the past. We report the difficult treatment of a 28-year-old schizophrenic woman. Psychotic symptoms were found resistant to monotherapy with clozapine or ziprasidone. In contrast, combined application led to a marked improvement in both positive and negative symptoms of schizophrenia along with a decrease of side effects.The reported combination is a promising option in cases of treatment-resistant schizophrenia and should be further evaluated in prospective studies.
SN - 0885-6222
UR - https://www.unboundmedicine.com/medline/citation/15181656/Combination_of_ziprasidone_and_clozapine_in_treatment_resistant_schizophrenia_
L2 - https://doi.org/10.1002/hup.580
DB - PRIME
DP - Unbound Medicine
ER -