TY - JOUR T1 - [Role of immediate hypersensitivity to airborne allergens in the pathogenesis of atopic dermatitis]. AU - Silny,Paweł, AU - Czarnecka-Operacz,Magdalena, AU - Silny,Wojciech, PY - 2004/6/12/pubmed PY - 2004/7/9/medline PY - 2004/6/12/entrez SP - 245 EP - 50 JF - Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego JO - Pol Merkur Lekarski VL - 16 IS - 93 N2 - UNLABELLED: Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with hyperproduction of immunoglobulin E directed against common environmental allergens. OBJECTIVES: The aim of the study was to evaluate the immediate type of immunological reaction indicated by airborne allergens in the pathomechanism of atopic dermatitis. MATERIAL AND METHODS: 529 patients with AD aged (0.5-60 years) who fulfilled basic Hanifin and Rajka criterias and 60 healthy volunteers in the control group were investigated. In order to evaluate IgE-mediated allergy to common airborne and alimentary allergens skin prick tests (SPT) were performed (26 airborne and 7 basic alimentary allergens) and concentration of serum antigen specific IgE (asigE) was measured. RESULTS: Our results indicated airborne allergy in case of 405 patients (76.6%) and food allergy only in 67 cases (12.7%). In the group of children aged 0.5-4 years food allergy was predominant but later on the predominance of airborne allergy was observed. CONCLUSIONS: We conclude that airborne allergy plays an important and predominant role in the pathomechanism of atopic dermatitis. SN - 1426-9686 UR - https://www.unboundmedicine.com/medline/citation/15190601/[Role_of_immediate_hypersensitivity_to_airborne_allergens_in_the_pathogenesis_of_atopic_dermatitis]_ DB - PRIME DP - Unbound Medicine ER -