Tags

Type your tag names separated by a space and hit enter

Outbreaks of acute gastroenteritis on cruise ships and on land: identification of a predominant circulating strain of norovirus--United States, 2002.
J Infect Dis. 2004 Jul 01; 190(1):27-36.JI

Abstract

In 2002, a sharp increase in outbreaks of norovirus-associated illness, both on cruise ships and on land, encouraged us to examine the molecular epidemiology of detected noroviruses, to identify a common strain or source. Of 14 laboratory-confirmed outbreaks on cruise ships, 12 (86%) were attributed to caliciviruses; among these 12, outbreak characteristics included continuation on successive cruises in 6 (50%), multiple modes of transmission in 7 (58%), and high (>10%) attack rates in 7 (58%). Eleven of the 12 calicivirus outbreaks were attributed to noroviruses, 7 (64%) of which were attributed to a previously unreported lineage, provisionally named "the Farmington Hills strain." From May 2002 to December 2002, 10 (45%) of 22 land-based outbreaks also were attributed to this strain. Nucleotide-sequence analysis provided insights into norovirus transmission, by documenting links among outbreaks, the introduction of strains onto ships, and viral persistence on board (despite cleaning). Control measures for outbreaks should address all routes of transmission. Better outbreak surveillance and collection of data on sequences will help to monitor norovirus strains and to identify common sources.

Authors+Show Affiliations

Atlanta Research and Education Foundation and National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. zux5@cdc.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15195240

Citation

Widdowson, Marc-Alain, et al. "Outbreaks of Acute Gastroenteritis On Cruise Ships and On Land: Identification of a Predominant Circulating Strain of norovirus--United States, 2002." The Journal of Infectious Diseases, vol. 190, no. 1, 2004, pp. 27-36.
Widdowson MA, Cramer EH, Hadley L, et al. Outbreaks of acute gastroenteritis on cruise ships and on land: identification of a predominant circulating strain of norovirus--United States, 2002. J Infect Dis. 2004;190(1):27-36.
Widdowson, M. A., Cramer, E. H., Hadley, L., Bresee, J. S., Beard, R. S., Bulens, S. N., Charles, M., Chege, W., Isakbaeva, E., Wright, J. G., Mintz, E., Forney, D., Massey, J., Glass, R. I., & Monroe, S. S. (2004). Outbreaks of acute gastroenteritis on cruise ships and on land: identification of a predominant circulating strain of norovirus--United States, 2002. The Journal of Infectious Diseases, 190(1), 27-36.
Widdowson MA, et al. Outbreaks of Acute Gastroenteritis On Cruise Ships and On Land: Identification of a Predominant Circulating Strain of norovirus--United States, 2002. J Infect Dis. 2004 Jul 1;190(1):27-36. PubMed PMID: 15195240.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outbreaks of acute gastroenteritis on cruise ships and on land: identification of a predominant circulating strain of norovirus--United States, 2002. AU - Widdowson,Marc-Alain, AU - Cramer,Elaine H, AU - Hadley,Leslie, AU - Bresee,Joseph S, AU - Beard,R Suzanne, AU - Bulens,Sandra N, AU - Charles,Myrna, AU - Chege,Wairimu, AU - Isakbaeva,Elmira, AU - Wright,Jennifer G, AU - Mintz,Eric, AU - Forney,David, AU - Massey,Jeffrey, AU - Glass,Roger I, AU - Monroe,Stephan S, Y1 - 2004/06/08/ PY - 2003/10/18/received PY - 2003/12/05/accepted PY - 2004/6/15/pubmed PY - 2004/8/4/medline PY - 2004/6/15/entrez SP - 27 EP - 36 JF - The Journal of infectious diseases JO - J Infect Dis VL - 190 IS - 1 N2 - In 2002, a sharp increase in outbreaks of norovirus-associated illness, both on cruise ships and on land, encouraged us to examine the molecular epidemiology of detected noroviruses, to identify a common strain or source. Of 14 laboratory-confirmed outbreaks on cruise ships, 12 (86%) were attributed to caliciviruses; among these 12, outbreak characteristics included continuation on successive cruises in 6 (50%), multiple modes of transmission in 7 (58%), and high (>10%) attack rates in 7 (58%). Eleven of the 12 calicivirus outbreaks were attributed to noroviruses, 7 (64%) of which were attributed to a previously unreported lineage, provisionally named "the Farmington Hills strain." From May 2002 to December 2002, 10 (45%) of 22 land-based outbreaks also were attributed to this strain. Nucleotide-sequence analysis provided insights into norovirus transmission, by documenting links among outbreaks, the introduction of strains onto ships, and viral persistence on board (despite cleaning). Control measures for outbreaks should address all routes of transmission. Better outbreak surveillance and collection of data on sequences will help to monitor norovirus strains and to identify common sources. SN - 0022-1899 UR - https://www.unboundmedicine.com/medline/citation/15195240/Outbreaks_of_acute_gastroenteritis_on_cruise_ships_and_on_land:_identification_of_a_predominant_circulating_strain_of_norovirus__United_States_2002_ L2 - https://academic.oup.com/jid/article-lookup/doi/10.1086/420888 DB - PRIME DP - Unbound Medicine ER -