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Effect of nutritional status on clinical outcome in a population of geriatric rehabilitation patients.
Aging Clin Exp Res 2004; 16(2):132-8AC

Abstract

BACKGROUND AND AIMS

In a geriatric patient, nutritional status (NS), particularly in the case of malnutrition (M), may influence not only clinical results but also achievement of targets expected by geriatric rehabilitation. The aim of this study was to evaluate the effect of nutritional status (NS) on the occurrence of Adverse Clinical Events (ACE) and on mortality in geriatric rehabilitation patients.

METHODS

We retrospectively examined the clinical records of 278 elderly subjects (154 women, 124 men), admitted to a geriatric hospital between September 2000 and December 2001 and evaluated for clinical, functional, cognitive and NS within the first 48 hours of admission. Clinical outcomes (ACE, mortality) were recorded during follow-up. Logistic regression analysis estimated models having mortality or the occurrence of ACE as outcome variables.

RESULTS

Malnutrition was detected upon admission in 56.1% of the sample population. Incidence of ACE in malnourished subjects was higher than that in well-nourished patients (28.2 vs 13.1%). Equally, mortality among malnourished subjects was higher than among those whose NS was normal (23.1 vs 9.8%). The logistic regression models were able to predict: 1) mortality from comorbidity (OR 1.43; 95% CI 1.16-1.78; p=0.001) and NS (OR 2.64; 95% CI 1.29-5.4; p=0.008), and 2) occurrence of ACE from comorbidity (OR 1.69; 95% CI 1.36-2.1; p=0.000), cognitive (OR 1.22; 95% CI 1.11-1.35; p=0.000) and nutritional status (OR 2.38; 95% CI 1.19-4.8; p=0.015).

CONCLUSIONS

NS emerged as the main independent predictor of both mortality and occurrence of ACE. Although most patients fell into the category of mild/moderate (energy) malnutrition (148/156), a mild deterioration of NS, for instance, reduction in triceps skinfold thickness (TSF) seemed to be sufficient to cause an increase in the incidence of ACE and in mortality.

Authors+Show Affiliations

Istituto di Scienza dell'Alimentazione, Università La Sapienza, Roma, Italy. lorenzomaria.donini@uniroma1.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15195988

Citation

Donini, Lorenzo M., et al. "Effect of Nutritional Status On Clinical Outcome in a Population of Geriatric Rehabilitation Patients." Aging Clinical and Experimental Research, vol. 16, no. 2, 2004, pp. 132-8.
Donini LM, De Bernardini L, De Felice MR, et al. Effect of nutritional status on clinical outcome in a population of geriatric rehabilitation patients. Aging Clin Exp Res. 2004;16(2):132-8.
Donini, L. M., De Bernardini, L., De Felice, M. R., Savina, C., Coletti, C., & Cannella, C. (2004). Effect of nutritional status on clinical outcome in a population of geriatric rehabilitation patients. Aging Clinical and Experimental Research, 16(2), pp. 132-8.
Donini LM, et al. Effect of Nutritional Status On Clinical Outcome in a Population of Geriatric Rehabilitation Patients. Aging Clin Exp Res. 2004;16(2):132-8. PubMed PMID: 15195988.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of nutritional status on clinical outcome in a population of geriatric rehabilitation patients. AU - Donini,Lorenzo M, AU - De Bernardini,Laura, AU - De Felice,Maria Rosaria, AU - Savina,Claudia, AU - Coletti,Cecilia, AU - Cannella,Carlo, PY - 2004/6/16/pubmed PY - 2005/1/15/medline PY - 2004/6/16/entrez SP - 132 EP - 8 JF - Aging clinical and experimental research JO - Aging Clin Exp Res VL - 16 IS - 2 N2 - BACKGROUND AND AIMS: In a geriatric patient, nutritional status (NS), particularly in the case of malnutrition (M), may influence not only clinical results but also achievement of targets expected by geriatric rehabilitation. The aim of this study was to evaluate the effect of nutritional status (NS) on the occurrence of Adverse Clinical Events (ACE) and on mortality in geriatric rehabilitation patients. METHODS: We retrospectively examined the clinical records of 278 elderly subjects (154 women, 124 men), admitted to a geriatric hospital between September 2000 and December 2001 and evaluated for clinical, functional, cognitive and NS within the first 48 hours of admission. Clinical outcomes (ACE, mortality) were recorded during follow-up. Logistic regression analysis estimated models having mortality or the occurrence of ACE as outcome variables. RESULTS: Malnutrition was detected upon admission in 56.1% of the sample population. Incidence of ACE in malnourished subjects was higher than that in well-nourished patients (28.2 vs 13.1%). Equally, mortality among malnourished subjects was higher than among those whose NS was normal (23.1 vs 9.8%). The logistic regression models were able to predict: 1) mortality from comorbidity (OR 1.43; 95% CI 1.16-1.78; p=0.001) and NS (OR 2.64; 95% CI 1.29-5.4; p=0.008), and 2) occurrence of ACE from comorbidity (OR 1.69; 95% CI 1.36-2.1; p=0.000), cognitive (OR 1.22; 95% CI 1.11-1.35; p=0.000) and nutritional status (OR 2.38; 95% CI 1.19-4.8; p=0.015). CONCLUSIONS: NS emerged as the main independent predictor of both mortality and occurrence of ACE. Although most patients fell into the category of mild/moderate (energy) malnutrition (148/156), a mild deterioration of NS, for instance, reduction in triceps skinfold thickness (TSF) seemed to be sufficient to cause an increase in the incidence of ACE and in mortality. SN - 1594-0667 UR - https://www.unboundmedicine.com/medline/citation/15195988/Effect_of_nutritional_status_on_clinical_outcome_in_a_population_of_geriatric_rehabilitation_patients_ L2 - https://medlineplus.gov/malnutrition.html DB - PRIME DP - Unbound Medicine ER -