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Detection of deep vein thrombosis with impedance plethysmography and real-time compression ultrasonography in hospitalized patients.
Arch Intern Med. 1992 Sep; 152(9):1901-3.AI

Abstract

BACKGROUND

Serial testing with impedance plethysmography or compression ultrasonography has been demonstrated to be feasible and accurate for the detection of deep vein thrombosis (DVT) in symptomatic outpatients, and these techniques are replacing contrast venography in this patient category. Limited data, however, are available on the clinical utility of these noninvasive tests in symptomatic hospitalized patients. The objectives of our study were to determine the feasibility of ascending contrast venography and to evaluate the accuracy of these two noninvasive methods for the detection of DVT in symptomatic hospitalized patients.

METHODS

A prospective, "blind" comparison of impedance plethysmography and compression ultrasonography with ascending contrast venography was performed in consecutive hospitalized patients with clinically suspected DVT of the leg.

RESULTS

Of the 127 potentially eligible patients, 44 had to be excluded; 25 of these could not undergo venography (feasibility of venography, 80.3%). The sensitivity, specificity, and positive and negative predictive values of impedance plethysmography for proximal DVT were 96%, 83%, 82%, and 97%, respectively. For compression ultrasonography, these measures for proximal DVT were 97%, 86%, 87%, and 97%, respectively. The overall prevalence of DVT was 53%, of which 85% was located proximally.

CONCLUSIONS

Contrast venography cannot be performed in about 20% of consecutive symptomatic patients. Both impedance plethysmography and compression ultrasonography are feasible and valid alternatives to contrast venography in the diagnostic treatment of these patients.

Authors+Show Affiliations

Heijboer H
Centre for Haemostasis, Thrombosis, Atherosclerosis and Inflammation Research, Academic Medical Centre, Amsterdam, The Netherlands.
Cogo A
No affiliation info available
Büller HR
No affiliation info available
Prandoni P
No affiliation info available
ten Cate JW
No affiliation info available

MeSH

Feasibility StudiesFemaleFemoral VeinHospitalizationHumansMaleMiddle AgedPhlebographyPlethysmography, ImpedancePopliteal VeinPredictive Value of TestsProspective StudiesSensitivity and SpecificityThrombosisUltrasonography

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1520059

Citation

Heijboer, H, et al. "Detection of Deep Vein Thrombosis With Impedance Plethysmography and Real-time Compression Ultrasonography in Hospitalized Patients." Archives of Internal Medicine, vol. 152, no. 9, 1992, pp. 1901-3.
Heijboer H, Cogo A, Büller HR, et al. Detection of deep vein thrombosis with impedance plethysmography and real-time compression ultrasonography in hospitalized patients. Arch Intern Med. 1992;152(9):1901-3.
Heijboer, H., Cogo, A., Büller, H. R., Prandoni, P., & ten Cate, J. W. (1992). Detection of deep vein thrombosis with impedance plethysmography and real-time compression ultrasonography in hospitalized patients. Archives of Internal Medicine, 152(9), 1901-3.
Heijboer H, et al. Detection of Deep Vein Thrombosis With Impedance Plethysmography and Real-time Compression Ultrasonography in Hospitalized Patients. Arch Intern Med. 1992;152(9):1901-3. PubMed PMID: 1520059.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Detection of deep vein thrombosis with impedance plethysmography and real-time compression ultrasonography in hospitalized patients. AU - Heijboer,H, AU - Cogo,A, AU - Büller,H R, AU - Prandoni,P, AU - ten Cate,J W, PY - 1992/9/1/pubmed PY - 1992/9/1/medline PY - 1992/9/1/entrez SP - 1901 EP - 3 JF - Archives of internal medicine JO - Arch Intern Med VL - 152 IS - 9 N2 - BACKGROUND: Serial testing with impedance plethysmography or compression ultrasonography has been demonstrated to be feasible and accurate for the detection of deep vein thrombosis (DVT) in symptomatic outpatients, and these techniques are replacing contrast venography in this patient category. Limited data, however, are available on the clinical utility of these noninvasive tests in symptomatic hospitalized patients. The objectives of our study were to determine the feasibility of ascending contrast venography and to evaluate the accuracy of these two noninvasive methods for the detection of DVT in symptomatic hospitalized patients. METHODS: A prospective, "blind" comparison of impedance plethysmography and compression ultrasonography with ascending contrast venography was performed in consecutive hospitalized patients with clinically suspected DVT of the leg. RESULTS: Of the 127 potentially eligible patients, 44 had to be excluded; 25 of these could not undergo venography (feasibility of venography, 80.3%). The sensitivity, specificity, and positive and negative predictive values of impedance plethysmography for proximal DVT were 96%, 83%, 82%, and 97%, respectively. For compression ultrasonography, these measures for proximal DVT were 97%, 86%, 87%, and 97%, respectively. The overall prevalence of DVT was 53%, of which 85% was located proximally. CONCLUSIONS: Contrast venography cannot be performed in about 20% of consecutive symptomatic patients. Both impedance plethysmography and compression ultrasonography are feasible and valid alternatives to contrast venography in the diagnostic treatment of these patients. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/1520059/Detection_of_deep_vein_thrombosis_with_impedance_plethysmography_and_real_time_compression_ultrasonography_in_hospitalized_patients_ DB - PRIME DP - Unbound Medicine ER -