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[Study of regional cerebral blood flow around hematoma in acute intracerebral hemorrhage by xenon-CT].
Zhonghua Yi Xue Za Zhi. 2004 May 17; 84(10):822-5.ZY

Abstract

OBJECTIVE

To study the change of regional cerebral blood flow (rCBF) around hematoma in acute intracerebral hemorrhage.

METHODS

Xenon-CT was performed on 5 patients of basal ganglia hemorrhage with the hematoma volume less than 30 ml, 3 males and 2 females, aged 56.8 +/- 5.6. within 36 hours of the onset and 13 days after to measure the rCBF was measured by 27 pixel rings respectively in the core of hematoma, edema region around the hematoma and compared with rCBF in the uninvolved hemisphere.

RESULTS

(1) all the 5 patients had a history of hypertension, the mean intracerebral hemorrhage volume was 13 ml +/- 7 ml (6.4 approximately 23.7 ml). The first examination was conducted 23 h +/- 6 h (19 approximately 34 h) after the onset and the second examination was conducted 13.0 d +/- 0.7 d (12 approximately 14 d) after the onset. (2) Within 36 hours of the onset, the mean rCBF in the core of hematoma was 15 ml.100 g(-1).min(-1) +/- 8 ml.100 g(-1).min(-1), and the mean rCBF in edema region around the hematoma was 30 ml.100 g(-1).min(-1) +/- 8 ml.100 g(-1).min(-1). Thirteen days after the onset the mean rCBF in the core of hematoma was 9 ml.100 g(-1).min(-1) +/- 4 ml.100 g(-1).min(-1), significantly reduced in comparison with that measured in the first examination (P = 0.014), and the mean rCBF in the edema region around the hematoma was 23 ml.100 g(-1).min(-1) +/- 13 ml.100 g(-1).min(-1), reduced in comparison with those measured in the first examination too, however, not significantly (P = 0.055). The rCBF reduction was more significant in the edema region adjacent to the hematoma (P = 0.004), but not in the distant edema region. During the first examination the rCBF in the edema region around the hematoma was lower than the enantiomorph rCBF by 20.9%. Thirteen days after, the rCBF in the edema region around the hematoma was lower than the enantiomorph rCBF by 46.3%, significantly greater than the reduction during the first examination (P = 0.324). There was no difference between the values of enantiomorph rCBF during the first and second examinations (P = 0.038).

CONCLUSION

There exists reduced perihematoma rCBF after intracerebral hemorrhage by xenon-CT examination, this phenomenon lasts 14 days and have the tendency of further reduced.

Authors+Show Affiliations

Department of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

15200884

Citation

Dong, Qiang, et al. "[Study of Regional Cerebral Blood Flow Around Hematoma in Acute Intracerebral Hemorrhage By Xenon-CT]." Zhonghua Yi Xue Za Zhi, vol. 84, no. 10, 2004, pp. 822-5.
Dong Q, Ding HY, Shi LF, et al. [Study of regional cerebral blood flow around hematoma in acute intracerebral hemorrhage by xenon-CT]. Zhonghua Yi Xue Za Zhi. 2004;84(10):822-5.
Dong, Q., Ding, H. Y., Shi, L. F., Han, X., Fu, J. H., & Lu, C. Z. (2004). [Study of regional cerebral blood flow around hematoma in acute intracerebral hemorrhage by xenon-CT]. Zhonghua Yi Xue Za Zhi, 84(10), 822-5.
Dong Q, et al. [Study of Regional Cerebral Blood Flow Around Hematoma in Acute Intracerebral Hemorrhage By Xenon-CT]. Zhonghua Yi Xue Za Zhi. 2004 May 17;84(10):822-5. PubMed PMID: 15200884.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Study of regional cerebral blood flow around hematoma in acute intracerebral hemorrhage by xenon-CT]. AU - Dong,Qiang, AU - Ding,Hong-yan, AU - Shi,Lang-feng, AU - Han,Xiang, AU - Fu,Jian-hui, AU - Lu,Chuan-zhen, PY - 2004/6/18/pubmed PY - 2004/11/13/medline PY - 2004/6/18/entrez SP - 822 EP - 5 JF - Zhonghua yi xue za zhi JO - Zhonghua Yi Xue Za Zhi VL - 84 IS - 10 N2 - OBJECTIVE: To study the change of regional cerebral blood flow (rCBF) around hematoma in acute intracerebral hemorrhage. METHODS: Xenon-CT was performed on 5 patients of basal ganglia hemorrhage with the hematoma volume less than 30 ml, 3 males and 2 females, aged 56.8 +/- 5.6. within 36 hours of the onset and 13 days after to measure the rCBF was measured by 27 pixel rings respectively in the core of hematoma, edema region around the hematoma and compared with rCBF in the uninvolved hemisphere. RESULTS: (1) all the 5 patients had a history of hypertension, the mean intracerebral hemorrhage volume was 13 ml +/- 7 ml (6.4 approximately 23.7 ml). The first examination was conducted 23 h +/- 6 h (19 approximately 34 h) after the onset and the second examination was conducted 13.0 d +/- 0.7 d (12 approximately 14 d) after the onset. (2) Within 36 hours of the onset, the mean rCBF in the core of hematoma was 15 ml.100 g(-1).min(-1) +/- 8 ml.100 g(-1).min(-1), and the mean rCBF in edema region around the hematoma was 30 ml.100 g(-1).min(-1) +/- 8 ml.100 g(-1).min(-1). Thirteen days after the onset the mean rCBF in the core of hematoma was 9 ml.100 g(-1).min(-1) +/- 4 ml.100 g(-1).min(-1), significantly reduced in comparison with that measured in the first examination (P = 0.014), and the mean rCBF in the edema region around the hematoma was 23 ml.100 g(-1).min(-1) +/- 13 ml.100 g(-1).min(-1), reduced in comparison with those measured in the first examination too, however, not significantly (P = 0.055). The rCBF reduction was more significant in the edema region adjacent to the hematoma (P = 0.004), but not in the distant edema region. During the first examination the rCBF in the edema region around the hematoma was lower than the enantiomorph rCBF by 20.9%. Thirteen days after, the rCBF in the edema region around the hematoma was lower than the enantiomorph rCBF by 46.3%, significantly greater than the reduction during the first examination (P = 0.324). There was no difference between the values of enantiomorph rCBF during the first and second examinations (P = 0.038). CONCLUSION: There exists reduced perihematoma rCBF after intracerebral hemorrhage by xenon-CT examination, this phenomenon lasts 14 days and have the tendency of further reduced. SN - 0376-2491 UR - https://www.unboundmedicine.com/medline/citation/15200884/[Study_of_regional_cerebral_blood_flow_around_hematoma_in_acute_intracerebral_hemorrhage_by_xenon_CT]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&issn=0376-2491&year=2004&vol=84&issue=10&fpage=822 DB - PRIME DP - Unbound Medicine ER -