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Amphetamines and 3,4-methylendioxymetamphetamine (MDMA): evaluation of KIMS (kinetic interaction of microparticles in solution) assay at two cut-off levels.
Clin Chem Lab Med 2004; 42(5):543-8CC

Abstract

Two screening methods for the assay of amphetamines and their derivatives have been applied to the same analytical instrument for their evaluation. In addition to an assay at a cut-off of 1000 microg/l, a new specific reagent was evaluated for an ultra-sensitive assay of amphetamines and 3,4-methylendioxymetamphetamine with a cut-off of 300 microg/l. The assay confirmation was performed using high-performance liquid chromatography and gas chromatography/ mass spectrometry techniques. The results were positive for both screening methods, confirming the efficacy of two simultaneous methods with different cut-off levels.

Authors+Show Affiliations

Department of Laboratory Medicine, University-Hospital of Padova, Padova, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Studies
Journal Article

Language

eng

PubMed ID

15202792

Citation

Marchioro, Lucio, et al. "Amphetamines and 3,4-methylendioxymetamphetamine (MDMA): Evaluation of KIMS (kinetic Interaction of Microparticles in Solution) Assay at Two Cut-off Levels." Clinical Chemistry and Laboratory Medicine, vol. 42, no. 5, 2004, pp. 543-8.
Marchioro L, Bassetto F, Dall'Olio G, et al. Amphetamines and 3,4-methylendioxymetamphetamine (MDMA): evaluation of KIMS (kinetic interaction of microparticles in solution) assay at two cut-off levels. Clin Chem Lab Med. 2004;42(5):543-8.
Marchioro, L., Bassetto, F., Dall'Olio, G., Tedeschi, L., Castagna, F., & Plebani, M. (2004). Amphetamines and 3,4-methylendioxymetamphetamine (MDMA): evaluation of KIMS (kinetic interaction of microparticles in solution) assay at two cut-off levels. Clinical Chemistry and Laboratory Medicine, 42(5), pp. 543-8.
Marchioro L, et al. Amphetamines and 3,4-methylendioxymetamphetamine (MDMA): Evaluation of KIMS (kinetic Interaction of Microparticles in Solution) Assay at Two Cut-off Levels. Clin Chem Lab Med. 2004;42(5):543-8. PubMed PMID: 15202792.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Amphetamines and 3,4-methylendioxymetamphetamine (MDMA): evaluation of KIMS (kinetic interaction of microparticles in solution) assay at two cut-off levels. AU - Marchioro,Lucio, AU - Bassetto,Flavia, AU - Dall'Olio,Giuliano, AU - Tedeschi,Luciano, AU - Castagna,Franca, AU - Plebani,Mario, PY - 2004/6/19/pubmed PY - 2005/1/19/medline PY - 2004/6/19/entrez SP - 543 EP - 8 JF - Clinical chemistry and laboratory medicine JO - Clin. Chem. Lab. Med. VL - 42 IS - 5 N2 - Two screening methods for the assay of amphetamines and their derivatives have been applied to the same analytical instrument for their evaluation. In addition to an assay at a cut-off of 1000 microg/l, a new specific reagent was evaluated for an ultra-sensitive assay of amphetamines and 3,4-methylendioxymetamphetamine with a cut-off of 300 microg/l. The assay confirmation was performed using high-performance liquid chromatography and gas chromatography/ mass spectrometry techniques. The results were positive for both screening methods, confirming the efficacy of two simultaneous methods with different cut-off levels. SN - 1434-6621 UR - https://www.unboundmedicine.com/medline/citation/15202792/Amphetamines_and_34_methylendioxymetamphetamine__MDMA_:_evaluation_of_KIMS__kinetic_interaction_of_microparticles_in_solution__assay_at_two_cut_off_levels_ L2 - https://www.degruyter.com/doi/10.1515/CCLM.2004.092 DB - PRIME DP - Unbound Medicine ER -