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Risk factors for non-fatal acute myocardial infarction in Italian women.
Prev Med. 2004 Jul; 39(1):128-34.PM

Abstract

BACKGROUND

We analyzed the relation between selected lifestyles and diseases and the risk of non-fatal acute myocardial infarction (AMI) in women in Northern Italy.

METHODS

We used a combined data set from three case-control studies, including 558 cases and 1,044 hospital controls.

RESULTS

The strongest risk factor for AMI was smoking, the odds ratio (OR) being 4.0 in current smokers (11.6 for > or = 5 cigarettes/day). Other risk factors were diabetes (OR 4.4), hypertension (OR 3.3), hyperlipidemia (OR 1.6), and family history of AMI (OR 2.1). Moderate alcohol drinking was protective (OR 0.8 for < 2 drinks/day) compared to non-drinkers, and heavy coffee drinking non-significantly increased the risk (OR 1.4 for >3 cups/day). Inverse association was found with fish (OR 0.7 for >1 portion/week), vegetables (0.7 for > or = 10 portions/week), and fruit (OR 0.6 for > or = 14 portions/week), while meat, whole-grain, and diary products were unrelated. Smoking effect was stronger in combination with diabetes (OR 27.7), hypertension (OR 15.7), hyperlipidemia (OR 6.3), family history of AMI (OR 8.7), and heavy coffee drinking (OR 5.7).

CONCLUSIONS

The strongest risk factor for AMI was smoking, responsible of about 37% of cases, followed by diabetes, hypertension, hyperlipidemia, family history of AMI. Avoidance of smoking and increasing fish, vegetables, and fruit would reduce AMI risk of about 50%.

Authors+Show Affiliations

Istituto di Ricerche Farmacologiche "Mario Negri", 20157 Milan, Italy. tavani@marionegri.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15207993

Citation

Tavani, Alessandra, et al. "Risk Factors for Non-fatal Acute Myocardial Infarction in Italian Women." Preventive Medicine, vol. 39, no. 1, 2004, pp. 128-34.
Tavani A, Bertuzzi M, Gallus S, et al. Risk factors for non-fatal acute myocardial infarction in Italian women. Prev Med. 2004;39(1):128-34.
Tavani, A., Bertuzzi, M., Gallus, S., Negri, E., & La Vecchia, C. (2004). Risk factors for non-fatal acute myocardial infarction in Italian women. Preventive Medicine, 39(1), 128-34.
Tavani A, et al. Risk Factors for Non-fatal Acute Myocardial Infarction in Italian Women. Prev Med. 2004;39(1):128-34. PubMed PMID: 15207993.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Risk factors for non-fatal acute myocardial infarction in Italian women. AU - Tavani,Alessandra, AU - Bertuzzi,Michaela, AU - Gallus,Silvano, AU - Negri,Eva, AU - La Vecchia,Carlo, PY - 2004/6/23/pubmed PY - 2004/10/13/medline PY - 2004/6/23/entrez SP - 128 EP - 34 JF - Preventive medicine JO - Prev Med VL - 39 IS - 1 N2 - BACKGROUND: We analyzed the relation between selected lifestyles and diseases and the risk of non-fatal acute myocardial infarction (AMI) in women in Northern Italy. METHODS: We used a combined data set from three case-control studies, including 558 cases and 1,044 hospital controls. RESULTS: The strongest risk factor for AMI was smoking, the odds ratio (OR) being 4.0 in current smokers (11.6 for > or = 5 cigarettes/day). Other risk factors were diabetes (OR 4.4), hypertension (OR 3.3), hyperlipidemia (OR 1.6), and family history of AMI (OR 2.1). Moderate alcohol drinking was protective (OR 0.8 for < 2 drinks/day) compared to non-drinkers, and heavy coffee drinking non-significantly increased the risk (OR 1.4 for >3 cups/day). Inverse association was found with fish (OR 0.7 for >1 portion/week), vegetables (0.7 for > or = 10 portions/week), and fruit (OR 0.6 for > or = 14 portions/week), while meat, whole-grain, and diary products were unrelated. Smoking effect was stronger in combination with diabetes (OR 27.7), hypertension (OR 15.7), hyperlipidemia (OR 6.3), family history of AMI (OR 8.7), and heavy coffee drinking (OR 5.7). CONCLUSIONS: The strongest risk factor for AMI was smoking, responsible of about 37% of cases, followed by diabetes, hypertension, hyperlipidemia, family history of AMI. Avoidance of smoking and increasing fish, vegetables, and fruit would reduce AMI risk of about 50%. SN - 0091-7435 UR - https://www.unboundmedicine.com/medline/citation/15207993/Risk_factors_for_non_fatal_acute_myocardial_infarction_in_Italian_women_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0091743504000428 DB - PRIME DP - Unbound Medicine ER -