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Exercise rehabilitation and skeletal muscle benefits in hemodialysis patients.
Clin Nephrol. 2004 May; 61 Suppl 1:S46-50.CN

Abstract

End-stage renal disease patients on hemodialysis (HD) are characterized by poor exercise tolerance and debilitation symptoms, despite advances in dialysis procedures and erythropoietin use. Specifically, the muscle strength and endurance are diminished, as result of skeletal muscle dysfunction and atrophy. These changes are presumed to be secondary to uremic toxins, anemia, malnutrition, deconditioning, neurohormonal insults and other disorders. Previous studies have shown that exercise training limits the pathophysiological changes that occur in HD patients, mainly regarding peripheral skeletal muscle. It is supported that significant peripheral adaptations to training occur, as evidenced by the improvement of muscle function. Especially, morphological and metabolic benefits in the skeletal muscles have been well-documented in HD patients following physical rehabilitation programs. Such beneficial adaptations increase endurance and muscle strength and contribute to improved work capacity. The better understanding of these adaptive mechanisms may allow for improved exercise training strategies in these patients.

Authors+Show Affiliations

Laboratory of Sports Medicine, Aristotle University of Thessaloniki, Greece. stergios@med.auth.gr

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15233247

Citation

Deligiannis, A. "Exercise Rehabilitation and Skeletal Muscle Benefits in Hemodialysis Patients." Clinical Nephrology, vol. 61 Suppl 1, 2004, pp. S46-50.
Deligiannis A. Exercise rehabilitation and skeletal muscle benefits in hemodialysis patients. Clin Nephrol. 2004;61 Suppl 1:S46-50.
Deligiannis, A. (2004). Exercise rehabilitation and skeletal muscle benefits in hemodialysis patients. Clinical Nephrology, 61 Suppl 1, S46-50.
Deligiannis A. Exercise Rehabilitation and Skeletal Muscle Benefits in Hemodialysis Patients. Clin Nephrol. 2004;61 Suppl 1:S46-50. PubMed PMID: 15233247.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Exercise rehabilitation and skeletal muscle benefits in hemodialysis patients. A1 - Deligiannis,A, PY - 2004/7/6/pubmed PY - 2004/9/24/medline PY - 2004/7/6/entrez SP - S46 EP - 50 JF - Clinical nephrology JO - Clin Nephrol VL - 61 Suppl 1 N2 - End-stage renal disease patients on hemodialysis (HD) are characterized by poor exercise tolerance and debilitation symptoms, despite advances in dialysis procedures and erythropoietin use. Specifically, the muscle strength and endurance are diminished, as result of skeletal muscle dysfunction and atrophy. These changes are presumed to be secondary to uremic toxins, anemia, malnutrition, deconditioning, neurohormonal insults and other disorders. Previous studies have shown that exercise training limits the pathophysiological changes that occur in HD patients, mainly regarding peripheral skeletal muscle. It is supported that significant peripheral adaptations to training occur, as evidenced by the improvement of muscle function. Especially, morphological and metabolic benefits in the skeletal muscles have been well-documented in HD patients following physical rehabilitation programs. Such beneficial adaptations increase endurance and muscle strength and contribute to improved work capacity. The better understanding of these adaptive mechanisms may allow for improved exercise training strategies in these patients. SN - 0301-0430 UR - https://www.unboundmedicine.com/medline/citation/15233247/Exercise_rehabilitation_and_skeletal_muscle_benefits_in_hemodialysis_patients_ L2 - https://medlineplus.gov/kidneyfailure.html DB - PRIME DP - Unbound Medicine ER -