Tags

Type your tag names separated by a space and hit enter

Photodynamic therapy with verteporfin for anterior segment neovascularizations in neovascular glaucoma.
Am J Ophthalmol. 2004 Jul; 138(1):157-8.AJ

Abstract

PURPOSE

To evaluate photodynamic therapy (PDT) with verteporfin for iris and angle neovascularization in eyes with neovascular glaucoma.

DESIGN

Interventional case series.

METHODS

A prospective, noncomparative case series included four patients (four eyes) with neovascular glaucoma. PDT was performed following the parameters of treatment of age-related macular degeneration with photodynamic therapy Study Group (TAP). The laser was directed at the anterior chamber angle and iris surface using a Goldmann three-mirror contact lens. Iris and angle neovascularization were quantified using the number of clock hours involved. Outcome measures were obliteration of neovascularization and decrease of intraocular pressure (IOP).

RESULTS

One week after PDT, we registered complete obliteration of angle neovascularization and partial occlusion of iris neovascularization. Subsequent reopening of angle neovascularization was detectable at 1 month. Intraocular pressure diminished considerably after 1 week, with a subsequent tendency toward stabilization.

CONCLUSIONS

Photodynamic therapy can be used safely and effectively in the early phases of neovascular glaucoma to achieve angle neovascularization obliteration and IOP reduction.

Authors+Show Affiliations

Eye Clinic, Ospedale Maggiore, University of Trieste, 34129 Trieste, Italy. maubp@yahoo.itNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15234305

Citation

Parodi, Maurizio Battaglia, and Pierluigi Iacono. "Photodynamic Therapy With Verteporfin for Anterior Segment Neovascularizations in Neovascular Glaucoma." American Journal of Ophthalmology, vol. 138, no. 1, 2004, pp. 157-8.
Parodi MB, Iacono P. Photodynamic therapy with verteporfin for anterior segment neovascularizations in neovascular glaucoma. Am J Ophthalmol. 2004;138(1):157-8.
Parodi, M. B., & Iacono, P. (2004). Photodynamic therapy with verteporfin for anterior segment neovascularizations in neovascular glaucoma. American Journal of Ophthalmology, 138(1), 157-8.
Parodi MB, Iacono P. Photodynamic Therapy With Verteporfin for Anterior Segment Neovascularizations in Neovascular Glaucoma. Am J Ophthalmol. 2004;138(1):157-8. PubMed PMID: 15234305.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Photodynamic therapy with verteporfin for anterior segment neovascularizations in neovascular glaucoma. AU - Parodi,Maurizio Battaglia, AU - Iacono,Pierluigi, PY - 2003/10/21/received PY - 2004/02/09/accepted PY - 2004/7/6/pubmed PY - 2004/9/1/medline PY - 2004/7/6/entrez SP - 157 EP - 8 JF - American journal of ophthalmology JO - Am J Ophthalmol VL - 138 IS - 1 N2 - PURPOSE: To evaluate photodynamic therapy (PDT) with verteporfin for iris and angle neovascularization in eyes with neovascular glaucoma. DESIGN: Interventional case series. METHODS: A prospective, noncomparative case series included four patients (four eyes) with neovascular glaucoma. PDT was performed following the parameters of treatment of age-related macular degeneration with photodynamic therapy Study Group (TAP). The laser was directed at the anterior chamber angle and iris surface using a Goldmann three-mirror contact lens. Iris and angle neovascularization were quantified using the number of clock hours involved. Outcome measures were obliteration of neovascularization and decrease of intraocular pressure (IOP). RESULTS: One week after PDT, we registered complete obliteration of angle neovascularization and partial occlusion of iris neovascularization. Subsequent reopening of angle neovascularization was detectable at 1 month. Intraocular pressure diminished considerably after 1 week, with a subsequent tendency toward stabilization. CONCLUSIONS: Photodynamic therapy can be used safely and effectively in the early phases of neovascular glaucoma to achieve angle neovascularization obliteration and IOP reduction. SN - 0002-9394 UR - https://www.unboundmedicine.com/medline/citation/15234305/Photodynamic_therapy_with_verteporfin_for_anterior_segment_neovascularizations_in_neovascular_glaucoma_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002939404001412 DB - PRIME DP - Unbound Medicine ER -