Abstract
PURPOSE
To evaluate photodynamic therapy (PDT) with verteporfin for iris and angle neovascularization in eyes with neovascular glaucoma.
DESIGN
Interventional case series.
METHODS
A prospective, noncomparative case series included four patients (four eyes) with neovascular glaucoma. PDT was performed following the parameters of treatment of age-related macular degeneration with photodynamic therapy Study Group (TAP). The laser was directed at the anterior chamber angle and iris surface using a Goldmann three-mirror contact lens. Iris and angle neovascularization were quantified using the number of clock hours involved. Outcome measures were obliteration of neovascularization and decrease of intraocular pressure (IOP).
RESULTS
One week after PDT, we registered complete obliteration of angle neovascularization and partial occlusion of iris neovascularization. Subsequent reopening of angle neovascularization was detectable at 1 month. Intraocular pressure diminished considerably after 1 week, with a subsequent tendency toward stabilization.
CONCLUSIONS
Photodynamic therapy can be used safely and effectively in the early phases of neovascular glaucoma to achieve angle neovascularization obliteration and IOP reduction.
TY - JOUR
T1 - Photodynamic therapy with verteporfin for anterior segment neovascularizations in neovascular glaucoma.
AU - Parodi,Maurizio Battaglia,
AU - Iacono,Pierluigi,
PY - 2003/10/21/received
PY - 2004/02/09/accepted
PY - 2004/7/6/pubmed
PY - 2004/9/1/medline
PY - 2004/7/6/entrez
SP - 157
EP - 8
JF - American journal of ophthalmology
JO - Am J Ophthalmol
VL - 138
IS - 1
N2 - PURPOSE: To evaluate photodynamic therapy (PDT) with verteporfin for iris and angle neovascularization in eyes with neovascular glaucoma. DESIGN: Interventional case series. METHODS: A prospective, noncomparative case series included four patients (four eyes) with neovascular glaucoma. PDT was performed following the parameters of treatment of age-related macular degeneration with photodynamic therapy Study Group (TAP). The laser was directed at the anterior chamber angle and iris surface using a Goldmann three-mirror contact lens. Iris and angle neovascularization were quantified using the number of clock hours involved. Outcome measures were obliteration of neovascularization and decrease of intraocular pressure (IOP). RESULTS: One week after PDT, we registered complete obliteration of angle neovascularization and partial occlusion of iris neovascularization. Subsequent reopening of angle neovascularization was detectable at 1 month. Intraocular pressure diminished considerably after 1 week, with a subsequent tendency toward stabilization. CONCLUSIONS: Photodynamic therapy can be used safely and effectively in the early phases of neovascular glaucoma to achieve angle neovascularization obliteration and IOP reduction.
SN - 0002-9394
UR - https://www.unboundmedicine.com/medline/citation/15234305/Photodynamic_therapy_with_verteporfin_for_anterior_segment_neovascularizations_in_neovascular_glaucoma_
L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002939404001412
DB - PRIME
DP - Unbound Medicine
ER -