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Role of oral food challenges in the diagnostic work-up of food allergy in atopic eczema dermatitis syndrome.
Allergy 2004; 59 Suppl 78:32-4A

Abstract

The diagnosis of food allergy in infants and children is still a challenging task for the pediatrician. While immediate-type allergic reactions to foods can be diagnosed quite easily, late-phase reactions, e.g. in atopic dermatitis, often represent a diagnostic challenge. Once classical diagnostic procedures such as history, skin prick tests, atopy patch test, and specific immunoglobulin E in serum have been exhausted, double-blind, placebo-controlled food challenges represent the state of the art. After an oligo-allergenic diet, suspected foods or placebo are given in a titrated manner until a clear clinical reaction or the highest dose. The observation period should be 48 h in the case of atopic dermatitis. Constant clinical monitoring is mandatory. Dietetic recommendations are given for 12 months. The effort involved in such a procedure is justified because it can help to avoid clinically relevant food allergens in some cases and in others can prevent children from being exposed unnecessarily to diets that may be harmful to them.

Authors+Show Affiliations

Department of Pediatric Pneumology and Immunology, University Children's Hospital Charité of Humboldt University, Berlin, Germany.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15245355

Citation

Niggemann, B. "Role of Oral Food Challenges in the Diagnostic Work-up of Food Allergy in Atopic Eczema Dermatitis Syndrome." Allergy, vol. 59 Suppl 78, 2004, pp. 32-4.
Niggemann B. Role of oral food challenges in the diagnostic work-up of food allergy in atopic eczema dermatitis syndrome. Allergy. 2004;59 Suppl 78:32-4.
Niggemann, B. (2004). Role of oral food challenges in the diagnostic work-up of food allergy in atopic eczema dermatitis syndrome. Allergy, 59 Suppl 78, pp. 32-4.
Niggemann B. Role of Oral Food Challenges in the Diagnostic Work-up of Food Allergy in Atopic Eczema Dermatitis Syndrome. Allergy. 2004;59 Suppl 78:32-4. PubMed PMID: 15245355.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Role of oral food challenges in the diagnostic work-up of food allergy in atopic eczema dermatitis syndrome. A1 - Niggemann,B, PY - 2004/7/13/pubmed PY - 2004/11/9/medline PY - 2004/7/13/entrez SP - 32 EP - 4 JF - Allergy JO - Allergy VL - 59 Suppl 78 N2 - The diagnosis of food allergy in infants and children is still a challenging task for the pediatrician. While immediate-type allergic reactions to foods can be diagnosed quite easily, late-phase reactions, e.g. in atopic dermatitis, often represent a diagnostic challenge. Once classical diagnostic procedures such as history, skin prick tests, atopy patch test, and specific immunoglobulin E in serum have been exhausted, double-blind, placebo-controlled food challenges represent the state of the art. After an oligo-allergenic diet, suspected foods or placebo are given in a titrated manner until a clear clinical reaction or the highest dose. The observation period should be 48 h in the case of atopic dermatitis. Constant clinical monitoring is mandatory. Dietetic recommendations are given for 12 months. The effort involved in such a procedure is justified because it can help to avoid clinically relevant food allergens in some cases and in others can prevent children from being exposed unnecessarily to diets that may be harmful to them. SN - 0105-4538 UR - https://www.unboundmedicine.com/medline/citation/15245355/Role_of_oral_food_challenges_in_the_diagnostic_work_up_of_food_allergy_in_atopic_eczema_dermatitis_syndrome_ L2 - http://www.diseaseinfosearch.org/result/9652 DB - PRIME DP - Unbound Medicine ER -