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Nutritional support in acute pancreatitis.
Curr Gastroenterol Rep. 2004 Aug; 6(4):320-6.CG

Abstract

Acute pancreatitis is one of the most catabolic of critical illnesses, and its clinical course is often prolonged. Consequently, the need for interventional nutritional support is great. Because of fears that feeding might exacerbate the tryptic autodigestion and disease process, total parenteral nutrition was used exclusively until recent years, when it was recognized that the complications of hyperglycemia and sepsis outweighed nutritional benefits. In clinical practice, enteral feeding has proven superior because it avoids these complications and maintains gut function, but enteral feeding needs to be given in a form that minimizes pancreatic stimulation. This review discusses the advances in our understanding of the pathophysiology of the disease, the results of recent clinical trials of nutritional support, and the challenges that remain in optimizing nutritional management.

Authors+Show Affiliations

Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, 200 Lothrop Street, PUH, Mezzanine Level, C Wing, Pittsburgh, PA 15213, USA. sjokeefe@pitt.eduNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Review

Language

eng

PubMed ID

15245702

Citation

Kaushik, Neeraj, and Stephen J D. O'Keefe. "Nutritional Support in Acute Pancreatitis." Current Gastroenterology Reports, vol. 6, no. 4, 2004, pp. 320-6.
Kaushik N, O'Keefe SJ. Nutritional support in acute pancreatitis. Curr Gastroenterol Rep. 2004;6(4):320-6.
Kaushik, N., & O'Keefe, S. J. (2004). Nutritional support in acute pancreatitis. Current Gastroenterology Reports, 6(4), 320-6.
Kaushik N, O'Keefe SJ. Nutritional Support in Acute Pancreatitis. Curr Gastroenterol Rep. 2004;6(4):320-6. PubMed PMID: 15245702.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nutritional support in acute pancreatitis. AU - Kaushik,Neeraj, AU - O'Keefe,Stephen J D, PY - 2004/7/13/pubmed PY - 2004/12/16/medline PY - 2004/7/13/entrez SP - 320 EP - 6 JF - Current gastroenterology reports JO - Curr Gastroenterol Rep VL - 6 IS - 4 N2 - Acute pancreatitis is one of the most catabolic of critical illnesses, and its clinical course is often prolonged. Consequently, the need for interventional nutritional support is great. Because of fears that feeding might exacerbate the tryptic autodigestion and disease process, total parenteral nutrition was used exclusively until recent years, when it was recognized that the complications of hyperglycemia and sepsis outweighed nutritional benefits. In clinical practice, enteral feeding has proven superior because it avoids these complications and maintains gut function, but enteral feeding needs to be given in a form that minimizes pancreatic stimulation. This review discusses the advances in our understanding of the pathophysiology of the disease, the results of recent clinical trials of nutritional support, and the challenges that remain in optimizing nutritional management. SN - 1522-8037 UR - https://www.unboundmedicine.com/medline/citation/15245702/Nutritional_support_in_acute_pancreatitis_ L2 - http://www.diseaseinfosearch.org/result/9663 DB - PRIME DP - Unbound Medicine ER -