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Premorbid cognitive and behavioral functioning in military recruits experiencing the first episode of psychosis.
CNS Spectr. 2004 Aug; 9(8):604-6.CS

Abstract

OBJECTIVE

To characterize the premorbid cognitive and behavioral abilities in apparently healthy adolescents who at a later time will be diagnosed with schizophreniform disorder or schizophrenia.

BACKGROUND

Clarifying the pathological relationship between subtle intellectual and behavioral abnormalities and disease could provide markers for the early prediction of future psychosis.

METHOD

Premorbid data on young male patients admitted to the Department of Psychiatry of the Central Military Hospital in Bucharest, Romania, between 1996 and 2002 and diagnosed with a first episode of psychosis or schizophreniform disorder were collected. The premorbid data consisted in the test scores of intellectual functioning and personality traits were collected by the Romanian Draft Board in order to assesses their aptitude to serve in the military. Premorbid cognitive and behavioral scores of male patients (cases=157) were compared with the scores of healthy male individuals (non-cases=169) matched for age, education, and geographic area of residence. The tests were administered when subjects were 18 years of age (initial screening) and the entire assessment was completed and concluded when subjects reached 20 years of age (actual conscription).

RESULTS

As a group, apparently healthy males later admitted for a first episode of psychosis or schizophreniform disorder, obtained lower (worse) scores on the Raven Progressive Matrices test and on relevant personality traits in comparison to controls.

CONCLUSION

The results add to the accumulating body of evidence suggesting that aspects of schizophrenia manifest years before the illness is formally diagnosed. Despite these results, more studies are needed to improve the diagnosing specificity and predictive value of the premorbid cognitive and behavioral manifestations, before they can be used as markers in models of primary or secondary prevention.

Authors+Show Affiliations

Department of Psychiatry, Carol Davilla School of Medicine, Bucharest, Romania. mihai.g@pcnet.roNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15273648

Citation

Gheorge, Mihai D., et al. "Premorbid Cognitive and Behavioral Functioning in Military Recruits Experiencing the First Episode of Psychosis." CNS Spectrums, vol. 9, no. 8, 2004, pp. 604-6.
Gheorge MD, Baloescu A, Grigorescu G. Premorbid cognitive and behavioral functioning in military recruits experiencing the first episode of psychosis. CNS Spectr. 2004;9(8):604-6.
Gheorge, M. D., Baloescu, A., & Grigorescu, G. (2004). Premorbid cognitive and behavioral functioning in military recruits experiencing the first episode of psychosis. CNS Spectrums, 9(8), 604-6.
Gheorge MD, Baloescu A, Grigorescu G. Premorbid Cognitive and Behavioral Functioning in Military Recruits Experiencing the First Episode of Psychosis. CNS Spectr. 2004;9(8):604-6. PubMed PMID: 15273648.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Premorbid cognitive and behavioral functioning in military recruits experiencing the first episode of psychosis. AU - Gheorge,Mihai D, AU - Baloescu,Alexandrina, AU - Grigorescu,Gabriela, PY - 2004/7/27/pubmed PY - 2004/12/16/medline PY - 2004/7/27/entrez SP - 604 EP - 6 JF - CNS spectrums JO - CNS Spectr VL - 9 IS - 8 N2 - OBJECTIVE: To characterize the premorbid cognitive and behavioral abilities in apparently healthy adolescents who at a later time will be diagnosed with schizophreniform disorder or schizophrenia. BACKGROUND: Clarifying the pathological relationship between subtle intellectual and behavioral abnormalities and disease could provide markers for the early prediction of future psychosis. METHOD: Premorbid data on young male patients admitted to the Department of Psychiatry of the Central Military Hospital in Bucharest, Romania, between 1996 and 2002 and diagnosed with a first episode of psychosis or schizophreniform disorder were collected. The premorbid data consisted in the test scores of intellectual functioning and personality traits were collected by the Romanian Draft Board in order to assesses their aptitude to serve in the military. Premorbid cognitive and behavioral scores of male patients (cases=157) were compared with the scores of healthy male individuals (non-cases=169) matched for age, education, and geographic area of residence. The tests were administered when subjects were 18 years of age (initial screening) and the entire assessment was completed and concluded when subjects reached 20 years of age (actual conscription). RESULTS: As a group, apparently healthy males later admitted for a first episode of psychosis or schizophreniform disorder, obtained lower (worse) scores on the Raven Progressive Matrices test and on relevant personality traits in comparison to controls. CONCLUSION: The results add to the accumulating body of evidence suggesting that aspects of schizophrenia manifest years before the illness is formally diagnosed. Despite these results, more studies are needed to improve the diagnosing specificity and predictive value of the premorbid cognitive and behavioral manifestations, before they can be used as markers in models of primary or secondary prevention. SN - 1092-8529 UR - https://www.unboundmedicine.com/medline/citation/15273648/Premorbid_cognitive_and_behavioral_functioning_in_military_recruits_experiencing_the_first_episode_of_psychosis_ L2 - https://medlineplus.gov/veteransandmilitaryhealth.html DB - PRIME DP - Unbound Medicine ER -