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Sebaceous carcinoma of the eyelid: a review of 14 cases.
Dermatol Surg. 2004 Aug; 30(8):1164-8.DS

Abstract

BACKGROUND

Sebaceous carcinoma of the eyelid is a rare tumor. Treatment can be complicated by noncontiguous spread of the tumor.

OBJECTIVE

Review a series of patients with sebaceous carcinoma to illustrate clinical presentations, treatments, and outcomes.

METHODS

We retrospectively reviewed medical records of patients with sebaceous carcinoma treated at Mayo Clinic (Rochester, MN).

RESULTS

Fourteen patients had sufficient follow-up data available for review. Mean follow-up was 57 months (range 18-134 months). Treatment included wide local excision with frozen and permanent section control (9 patients, 64%), Mohs micrographic surgery (2 patients, 14%), external beam radiation (2 patients, 14%), and exenteration and total parotidectomy with cervical lymph node dissection (1 patient, 7%). Two patients (14%) had local recurrence of the tumor after wide local excision, and 1 patient (7%) had tumor recurrence after Mohs micrographic surgery.

CONCLUSION

Treatment should be chosen on the basis of the extent of the tumor and the specific needs of the patient. The mainstay of treatment of tumors without orbital involvement has been wide local excision, with the margins checked in both permanent and frozen sections, in combination with conjunctival map biopsies when warranted. Mohs micrographic surgery is an alternative that may provide tissue conservation and lower recurrence rates. Recurrence rates between treatments are difficult to assess because of the small number of cases reported in the literature. In cases with orbital involvement, exenteration may be warranted. Radiation may be useful when surgery cannot be tolerated.

Authors+Show Affiliations

Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15274713

Citation

Callahan, Elizabeth F., et al. "Sebaceous Carcinoma of the Eyelid: a Review of 14 Cases." Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.], vol. 30, no. 8, 2004, pp. 1164-8.
Callahan EF, Appert DL, Roenigk RK, et al. Sebaceous carcinoma of the eyelid: a review of 14 cases. Dermatol Surg. 2004;30(8):1164-8.
Callahan, E. F., Appert, D. L., Roenigk, R. K., & Bartley, G. B. (2004). Sebaceous carcinoma of the eyelid: a review of 14 cases. Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.], 30(8), 1164-8.
Callahan EF, et al. Sebaceous Carcinoma of the Eyelid: a Review of 14 Cases. Dermatol Surg. 2004;30(8):1164-8. PubMed PMID: 15274713.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sebaceous carcinoma of the eyelid: a review of 14 cases. AU - Callahan,Elizabeth F, AU - Appert,David L, AU - Roenigk,Randall K, AU - Bartley,George B, PY - 2004/7/28/pubmed PY - 2004/9/3/medline PY - 2004/7/28/entrez SP - 1164 EP - 8 JF - Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] JO - Dermatol Surg VL - 30 IS - 8 N2 - BACKGROUND: Sebaceous carcinoma of the eyelid is a rare tumor. Treatment can be complicated by noncontiguous spread of the tumor. OBJECTIVE: Review a series of patients with sebaceous carcinoma to illustrate clinical presentations, treatments, and outcomes. METHODS: We retrospectively reviewed medical records of patients with sebaceous carcinoma treated at Mayo Clinic (Rochester, MN). RESULTS: Fourteen patients had sufficient follow-up data available for review. Mean follow-up was 57 months (range 18-134 months). Treatment included wide local excision with frozen and permanent section control (9 patients, 64%), Mohs micrographic surgery (2 patients, 14%), external beam radiation (2 patients, 14%), and exenteration and total parotidectomy with cervical lymph node dissection (1 patient, 7%). Two patients (14%) had local recurrence of the tumor after wide local excision, and 1 patient (7%) had tumor recurrence after Mohs micrographic surgery. CONCLUSION: Treatment should be chosen on the basis of the extent of the tumor and the specific needs of the patient. The mainstay of treatment of tumors without orbital involvement has been wide local excision, with the margins checked in both permanent and frozen sections, in combination with conjunctival map biopsies when warranted. Mohs micrographic surgery is an alternative that may provide tissue conservation and lower recurrence rates. Recurrence rates between treatments are difficult to assess because of the small number of cases reported in the literature. In cases with orbital involvement, exenteration may be warranted. Radiation may be useful when surgery cannot be tolerated. SN - 1076-0512 UR - https://www.unboundmedicine.com/medline/citation/15274713/Sebaceous_carcinoma_of_the_eyelid:_a_review_of_14_cases_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1076-0512&date=2004&volume=30&issue=8&spage=1164 DB - PRIME DP - Unbound Medicine ER -