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Itraconazole in the treatment of tinea capitis caused by Microsporum canis: experience in a large cohort.
Pediatr Dermatol. 2004 Jul-Aug; 21(4):499-502.PD

Abstract

Mycotic scalp infection caused by Microsporum canis is one of the more recalcitrant disorders, with increasing incidence during the last decade. We report our experience with administration of itraconazole in 163 children (86 girls, 77 boys) with M. canis tinea capitis. Fifty-five patients had previous treatment with terbinafine without success. In all children, the dosage of itraconazole was adjusted according to body weight, with 5 mg/kg/day given in a continuous regimen either as a capsule (116 patients) or an oral suspension (47 patients). In all children, there was both clinical and mycologic cure after a mean treatment period of 39 +/- 12 days (range 10-77 days). Eleven children (6.7%) had side effects: diarrhea in five children, cutaneous eruption in four, and abdominal pain in two. Itraconazole was effective and safe for the treatment of M. canis tinea capitis.

Authors+Show Affiliations

Department of Dermatology, University of Graz, Graz, Austria. gabriele.ginter@kfunigraz.ac.atNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

15283801

Citation

Ginter-Hanselmayer, Gabriele, et al. "Itraconazole in the Treatment of Tinea Capitis Caused By Microsporum Canis: Experience in a Large Cohort." Pediatric Dermatology, vol. 21, no. 4, 2004, pp. 499-502.
Ginter-Hanselmayer G, Smolle J, Gupta A. Itraconazole in the treatment of tinea capitis caused by Microsporum canis: experience in a large cohort. Pediatr Dermatol. 2004;21(4):499-502.
Ginter-Hanselmayer, G., Smolle, J., & Gupta, A. (2004). Itraconazole in the treatment of tinea capitis caused by Microsporum canis: experience in a large cohort. Pediatric Dermatology, 21(4), 499-502.
Ginter-Hanselmayer G, Smolle J, Gupta A. Itraconazole in the Treatment of Tinea Capitis Caused By Microsporum Canis: Experience in a Large Cohort. Pediatr Dermatol. 2004 Jul-Aug;21(4):499-502. PubMed PMID: 15283801.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Itraconazole in the treatment of tinea capitis caused by Microsporum canis: experience in a large cohort. AU - Ginter-Hanselmayer,Gabriele, AU - Smolle,Josef, AU - Gupta,Aditya, PY - 2004/7/31/pubmed PY - 2004/12/16/medline PY - 2004/7/31/entrez SP - 499 EP - 502 JF - Pediatric dermatology JO - Pediatr Dermatol VL - 21 IS - 4 N2 - Mycotic scalp infection caused by Microsporum canis is one of the more recalcitrant disorders, with increasing incidence during the last decade. We report our experience with administration of itraconazole in 163 children (86 girls, 77 boys) with M. canis tinea capitis. Fifty-five patients had previous treatment with terbinafine without success. In all children, the dosage of itraconazole was adjusted according to body weight, with 5 mg/kg/day given in a continuous regimen either as a capsule (116 patients) or an oral suspension (47 patients). In all children, there was both clinical and mycologic cure after a mean treatment period of 39 +/- 12 days (range 10-77 days). Eleven children (6.7%) had side effects: diarrhea in five children, cutaneous eruption in four, and abdominal pain in two. Itraconazole was effective and safe for the treatment of M. canis tinea capitis. SN - 0736-8046 UR - https://www.unboundmedicine.com/medline/citation/15283801/Itraconazole_in_the_treatment_of_tinea_capitis_caused_by_Microsporum_canis:_experience_in_a_large_cohort_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0736-8046&date=2004&volume=21&issue=4&spage=499 DB - PRIME DP - Unbound Medicine ER -