Tags

Type your tag names separated by a space and hit enter

Effect of HRT on hormone responses to resistance exercise in post-menopausal women.
Maturitas 2004; 48(4):360-71M

Abstract

PURPOSE

The purpose of this study was to evaluate the effect of hormone replacement therapy (HRT) on the acute and chronic hormonal responses to resistance exercise in post-menopausal women.

METHODS

Thirty-two post-menopausal women were recruited for this study; 16 who were currently using HRT and 16 who were not using HRT. Subjects in both the HRT and NHRT groups were randomly assigned to either a resistance training group (N = 16; 8 HRT and 8 NHRT) or a control group (N = 16; 8 HRT and 8 NHRT). The training group completed a supervised resistance training program three times a week for 12 weeks. To evaluate changes in hormone levels, resting blood samples were drawn at weeks 0, 4, and 13 of the program. In addition, at weeks 0 and 13, post-exercise blood samples were drawn in order to examine the hormone response to an acute bout of resistance exercise. Samples were analyzed for serum growth hormone (GH), insulin-like growth factor-1 (IGF-1), testosterone, estradiol, dehydroepiandrosterone (DHEA), and cortisol.

RESULTS

There were no significant changes in resting hormone levels between weeks 0, 4, and 13 of the training program. There was a significant week-by-group interaction for DHEA (P < 0.05) and cortisol (P < 0.05) with the NHRT-training group having a greater post-exercise increase in DHEA and cortisol after training. Overall, the post-exercise GH levels were significantly greater than pre-exercise (P < 0.05) or recovery levels (P < 0.01). There were no significant differences between HRT and NHRT groups in the acute hormone response to exercise.

CONCLUSION

These results indicate that HRT will not have an effect on the acute or chronic hormone response to a recreational resistance training program in post-menopausal women.

Authors+Show Affiliations

Department of Biology, University of New Brunswick, Fredericton, NB, Canada. jennifer.copeland@uleth.caNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15283928

Citation

Copeland, Jennifer L., and Mark S. Tremblay. "Effect of HRT On Hormone Responses to Resistance Exercise in Post-menopausal Women." Maturitas, vol. 48, no. 4, 2004, pp. 360-71.
Copeland JL, Tremblay MS. Effect of HRT on hormone responses to resistance exercise in post-menopausal women. Maturitas. 2004;48(4):360-71.
Copeland, J. L., & Tremblay, M. S. (2004). Effect of HRT on hormone responses to resistance exercise in post-menopausal women. Maturitas, 48(4), pp. 360-71.
Copeland JL, Tremblay MS. Effect of HRT On Hormone Responses to Resistance Exercise in Post-menopausal Women. Maturitas. 2004 Aug 20;48(4):360-71. PubMed PMID: 15283928.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of HRT on hormone responses to resistance exercise in post-menopausal women. AU - Copeland,Jennifer L, AU - Tremblay,Mark S, PY - 2003/02/06/received PY - 2003/08/26/revised PY - 2003/09/04/accepted PY - 2004/7/31/pubmed PY - 2005/1/6/medline PY - 2004/7/31/entrez SP - 360 EP - 71 JF - Maturitas JO - Maturitas VL - 48 IS - 4 N2 - PURPOSE: The purpose of this study was to evaluate the effect of hormone replacement therapy (HRT) on the acute and chronic hormonal responses to resistance exercise in post-menopausal women. METHODS: Thirty-two post-menopausal women were recruited for this study; 16 who were currently using HRT and 16 who were not using HRT. Subjects in both the HRT and NHRT groups were randomly assigned to either a resistance training group (N = 16; 8 HRT and 8 NHRT) or a control group (N = 16; 8 HRT and 8 NHRT). The training group completed a supervised resistance training program three times a week for 12 weeks. To evaluate changes in hormone levels, resting blood samples were drawn at weeks 0, 4, and 13 of the program. In addition, at weeks 0 and 13, post-exercise blood samples were drawn in order to examine the hormone response to an acute bout of resistance exercise. Samples were analyzed for serum growth hormone (GH), insulin-like growth factor-1 (IGF-1), testosterone, estradiol, dehydroepiandrosterone (DHEA), and cortisol. RESULTS: There were no significant changes in resting hormone levels between weeks 0, 4, and 13 of the training program. There was a significant week-by-group interaction for DHEA (P < 0.05) and cortisol (P < 0.05) with the NHRT-training group having a greater post-exercise increase in DHEA and cortisol after training. Overall, the post-exercise GH levels were significantly greater than pre-exercise (P < 0.05) or recovery levels (P < 0.01). There were no significant differences between HRT and NHRT groups in the acute hormone response to exercise. CONCLUSION: These results indicate that HRT will not have an effect on the acute or chronic hormone response to a recreational resistance training program in post-menopausal women. SN - 0378-5122 UR - https://www.unboundmedicine.com/medline/citation/15283928/Effect_of_HRT_on_hormone_responses_to_resistance_exercise_in_post_menopausal_women_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0378512203003542 DB - PRIME DP - Unbound Medicine ER -