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Epidural opioids for postoperative pain relief following hepatectomy.
Osaka City Med J. 1992 Jun; 38(1):67-77.OC

Abstract

Postoperative pain relief with epidural morphine or buprenorphine and intramuscular morphine was investigated in 67 patients undergoing hepatectomy. When the patient first complained of pain after surgery, 1 or 2mg of epidural morphine, or 0.06 mg of epidural buprenorphine given either at T 10-11 or L 3-4, or 0.1 mg/kg of morphine intramuscularly was administered. Lumbar epidural morphine 2mg, as well as thoracic epidural morphine 2mg, produced excellent and long-lasting pain relief. Nine of 12 patients receiving thoracic epidural buprenorphine 0.06 mg were completely pain-free. Thoracic epidural morphine 1 mg and lumbar epidural buprenorphine 0.06 mg produced incomplete analgesia. Analgesic duration of intramuscular morphine tended to be shorter than that of 2 mg of epidural morphine. PaCO2 increased significantly following thoracic epidural morphine 2 mg, although PaCO2 did not change after lumbar epidural morphine 2 mg. No patient had serious side effects. The lumbar epidural administration of 2 mg morphine may be recommended for postoperative analgesia following hepatectomy.

Authors+Show Affiliations

Yukioka H
Department of Anesthesiology and Intensive Care Medicine, Osaka City University Medical School, Japan.
Fujimori M
No affiliation info available

MeSH

AdultAgedBuprenorphineFemaleHepatectomyHumansInjections, EpiduralMaleMiddle AgedMorphinePain, Postoperative

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1528580

Citation

Yukioka, H, and M Fujimori. "Epidural Opioids for Postoperative Pain Relief Following Hepatectomy." Osaka City Medical Journal, vol. 38, no. 1, 1992, pp. 67-77.
Yukioka H, Fujimori M. Epidural opioids for postoperative pain relief following hepatectomy. Osaka City Med J. 1992;38(1):67-77.
Yukioka, H., & Fujimori, M. (1992). Epidural opioids for postoperative pain relief following hepatectomy. Osaka City Medical Journal, 38(1), 67-77.
Yukioka H, Fujimori M. Epidural Opioids for Postoperative Pain Relief Following Hepatectomy. Osaka City Med J. 1992;38(1):67-77. PubMed PMID: 1528580.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidural opioids for postoperative pain relief following hepatectomy. AU - Yukioka,H, AU - Fujimori,M, PY - 1992/6/1/pubmed PY - 1992/6/1/medline PY - 1992/6/1/entrez SP - 67 EP - 77 JF - Osaka city medical journal JO - Osaka City Med J VL - 38 IS - 1 N2 - Postoperative pain relief with epidural morphine or buprenorphine and intramuscular morphine was investigated in 67 patients undergoing hepatectomy. When the patient first complained of pain after surgery, 1 or 2mg of epidural morphine, or 0.06 mg of epidural buprenorphine given either at T 10-11 or L 3-4, or 0.1 mg/kg of morphine intramuscularly was administered. Lumbar epidural morphine 2mg, as well as thoracic epidural morphine 2mg, produced excellent and long-lasting pain relief. Nine of 12 patients receiving thoracic epidural buprenorphine 0.06 mg were completely pain-free. Thoracic epidural morphine 1 mg and lumbar epidural buprenorphine 0.06 mg produced incomplete analgesia. Analgesic duration of intramuscular morphine tended to be shorter than that of 2 mg of epidural morphine. PaCO2 increased significantly following thoracic epidural morphine 2 mg, although PaCO2 did not change after lumbar epidural morphine 2 mg. No patient had serious side effects. The lumbar epidural administration of 2 mg morphine may be recommended for postoperative analgesia following hepatectomy. SN - 0030-6096 UR - https://www.unboundmedicine.com/medline/citation/1528580/Epidural_opioids_for_postoperative_pain_relief_following_hepatectomy_ DB - PRIME DP - Unbound Medicine ER -