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Alopecia areata with lymphocytic mural folliculitis affecting the isthmus in a thoroughbred mare.
Vet Dermatol 2004; 15(4):260-5VD

Abstract

A 13-year-old, thoroughbred mare was presented with an 8-year history of multifocal, generalized, noninflammatory alopecia and a 3-month history of alopecia, erythema and scaling of the white star on the forehead and muzzle. Histopathological examination of biopsy samples from multiple sites on the body (mane, neck, shoulder, flank and gluteal region) showed a subtle lymphocytic inflammatory infiltrate affecting and surrounding the anagen hair bulbs, consistent with a diagnosis of alopecia areata. The biopsy sample from the star on the forehead showed atrophic hair follicles with perifollicular and mural mononuclear folliculitis affecting the isthmus. Immunohistochemical staining with a CD3 marker confirmed the T-lymphocytic origin of the inflammatory infiltrate in all the samples. The concurrent presence of lymphocytic infiltration at the bulbar and isthmic level of the hair follicles in the same horse is unusual. This finding may represent a variation of the histological appearance of alopecia areata.

Authors+Show Affiliations

Hospital for Small Animals, The University of Edinburgh, The Royal (Dick) School of Veterinary Studies, Easter Bush Veterinary Center, Roslin, Midlothian, EH25 9RG, UK.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

15305934

Citation

Colombo, Silvia, et al. "Alopecia Areata With Lymphocytic Mural Folliculitis Affecting the Isthmus in a Thoroughbred Mare." Veterinary Dermatology, vol. 15, no. 4, 2004, pp. 260-5.
Colombo S, Keen JA, Brownstein DG, et al. Alopecia areata with lymphocytic mural folliculitis affecting the isthmus in a thoroughbred mare. Vet Dermatol. 2004;15(4):260-5.
Colombo, S., Keen, J. A., Brownstein, D. G., Rhind, S. M., McGorum, B. C., & Hill, P. B. (2004). Alopecia areata with lymphocytic mural folliculitis affecting the isthmus in a thoroughbred mare. Veterinary Dermatology, 15(4), pp. 260-5.
Colombo S, et al. Alopecia Areata With Lymphocytic Mural Folliculitis Affecting the Isthmus in a Thoroughbred Mare. Vet Dermatol. 2004;15(4):260-5. PubMed PMID: 15305934.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alopecia areata with lymphocytic mural folliculitis affecting the isthmus in a thoroughbred mare. AU - Colombo,Silvia, AU - Keen,John A, AU - Brownstein,David G, AU - Rhind,Susan M, AU - McGorum,Bruce C, AU - Hill,Peter B, PY - 2004/8/13/pubmed PY - 2004/10/29/medline PY - 2004/8/13/entrez SP - 260 EP - 5 JF - Veterinary dermatology JO - Vet. Dermatol. VL - 15 IS - 4 N2 - A 13-year-old, thoroughbred mare was presented with an 8-year history of multifocal, generalized, noninflammatory alopecia and a 3-month history of alopecia, erythema and scaling of the white star on the forehead and muzzle. Histopathological examination of biopsy samples from multiple sites on the body (mane, neck, shoulder, flank and gluteal region) showed a subtle lymphocytic inflammatory infiltrate affecting and surrounding the anagen hair bulbs, consistent with a diagnosis of alopecia areata. The biopsy sample from the star on the forehead showed atrophic hair follicles with perifollicular and mural mononuclear folliculitis affecting the isthmus. Immunohistochemical staining with a CD3 marker confirmed the T-lymphocytic origin of the inflammatory infiltrate in all the samples. The concurrent presence of lymphocytic infiltration at the bulbar and isthmic level of the hair follicles in the same horse is unusual. This finding may represent a variation of the histological appearance of alopecia areata. SN - 0959-4493 UR - https://www.unboundmedicine.com/medline/citation/15305934/Alopecia_areata_with_lymphocytic_mural_folliculitis_affecting_the_isthmus_in_a_thoroughbred_mare_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0959-4493&date=2004&volume=15&issue=4&spage=260 DB - PRIME DP - Unbound Medicine ER -