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Role of the endocannabinoid system in Alzheimer's disease: new perspectives.
Life Sci. 2004 Sep 03; 75(16):1907-15.LS

Abstract

The role of the endocannabinoid system in several diseases is currently under intense study. Among these, Alzheimer's disease may be a new promising area of research. We have recently reported the existence of profound changes in the location and density of several elements of this system in Alzheimer's disease tissue samples, indicating that a non-neuronal endocannabinoid system is up-regulated in activated glia. Additional data from other groups suggest that glial cells may be important elements in the regulation of endocannabinoid system activity, both in health as in disease. Some of these aspects are briefly discussed in the present review.

Authors+Show Affiliations

Laboratorio de Apoyo a la Investigación, Fundación Hospital Alcorcón, c/ Budapest 1, 28922, Madrid, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

15306158

Citation

Pazos, M R., et al. "Role of the Endocannabinoid System in Alzheimer's Disease: New Perspectives." Life Sciences, vol. 75, no. 16, 2004, pp. 1907-15.
Pazos MR, Núñez E, Benito C, et al. Role of the endocannabinoid system in Alzheimer's disease: new perspectives. Life Sci. 2004;75(16):1907-15.
Pazos, M. R., Núñez, E., Benito, C., Tolón, R. M., & Romero, J. (2004). Role of the endocannabinoid system in Alzheimer's disease: new perspectives. Life Sciences, 75(16), 1907-15.
Pazos MR, et al. Role of the Endocannabinoid System in Alzheimer's Disease: New Perspectives. Life Sci. 2004 Sep 3;75(16):1907-15. PubMed PMID: 15306158.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Role of the endocannabinoid system in Alzheimer's disease: new perspectives. AU - Pazos,M R, AU - Núñez,E, AU - Benito,C, AU - Tolón,R M, AU - Romero,J, PY - 2004/02/03/received PY - 2004/03/26/accepted PY - 2004/8/13/pubmed PY - 2004/10/2/medline PY - 2004/8/13/entrez SP - 1907 EP - 15 JF - Life sciences JO - Life Sci. VL - 75 IS - 16 N2 - The role of the endocannabinoid system in several diseases is currently under intense study. Among these, Alzheimer's disease may be a new promising area of research. We have recently reported the existence of profound changes in the location and density of several elements of this system in Alzheimer's disease tissue samples, indicating that a non-neuronal endocannabinoid system is up-regulated in activated glia. Additional data from other groups suggest that glial cells may be important elements in the regulation of endocannabinoid system activity, both in health as in disease. Some of these aspects are briefly discussed in the present review. SN - 0024-3205 UR - https://www.unboundmedicine.com/medline/citation/15306158/Role_of_the_endocannabinoid_system_in_Alzheimer's_disease:_new_perspectives_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0024-3205(04)00560-0 DB - PRIME DP - Unbound Medicine ER -