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[Studies on antibacterial activities of secondary metabolites from fungus Cephalosporium sp. AL031].
Zhong Yao Cai. 2004 Apr; 27(4):270-2.ZY

Abstract

The antibacterial activity of fourteen identified compounds from secondary metabolites of fungus Cephalosporium sp. AL031 against eleven gram-positive or gram-negative bacteria in vitro was investigated by agar diffusion assay. The results suggested that two new compounds [S-(+)-5-hydroxymellein, S-(+)-7-hydroxymellein], together with four known compounds [S-(+)-mellein, 2,4-dihydroxy-3,6-dimethylbenzoic acid, 3,6-dihydroxy-2,4-dimethylbenzoic acid and succinic acid] had broad spectrum antibacterial activity. The minimum inhibitory concentrations (MIC) of these six compounds against Shigella sonnei, Mycobacterium tuberculosis and Streptococcus pneumoniae were determined. Their MIC were 0.03125 to approximately 0.5 mg/ml.

Authors+Show Affiliations

Yunnan Normal University, Kunming 650092.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

15307685

Citation

Yunmei, Bi, et al. "[Studies On Antibacterial Activities of Secondary Metabolites From Fungus Cephalosporium Sp. AL031]." Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials, vol. 27, no. 4, 2004, pp. 270-2.
Yunmei B, Lei B, Wei B, et al. [Studies on antibacterial activities of secondary metabolites from fungus Cephalosporium sp. AL031]. Zhong Yao Cai. 2004;27(4):270-2.
Yunmei, B., Lei, B., Wei, B., & Yanling, F. (2004). [Studies on antibacterial activities of secondary metabolites from fungus Cephalosporium sp. AL031]. Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials, 27(4), 270-2.
Yunmei B, et al. [Studies On Antibacterial Activities of Secondary Metabolites From Fungus Cephalosporium Sp. AL031]. Zhong Yao Cai. 2004;27(4):270-2. PubMed PMID: 15307685.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Studies on antibacterial activities of secondary metabolites from fungus Cephalosporium sp. AL031]. AU - Yunmei,Bi, AU - Lei,Bao, AU - Wei,Bao, AU - Yanling,Fan, PY - 2004/8/17/pubmed PY - 2005/2/18/medline PY - 2004/8/17/entrez SP - 270 EP - 2 JF - Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials JO - Zhong Yao Cai VL - 27 IS - 4 N2 - The antibacterial activity of fourteen identified compounds from secondary metabolites of fungus Cephalosporium sp. AL031 against eleven gram-positive or gram-negative bacteria in vitro was investigated by agar diffusion assay. The results suggested that two new compounds [S-(+)-5-hydroxymellein, S-(+)-7-hydroxymellein], together with four known compounds [S-(+)-mellein, 2,4-dihydroxy-3,6-dimethylbenzoic acid, 3,6-dihydroxy-2,4-dimethylbenzoic acid and succinic acid] had broad spectrum antibacterial activity. The minimum inhibitory concentrations (MIC) of these six compounds against Shigella sonnei, Mycobacterium tuberculosis and Streptococcus pneumoniae were determined. Their MIC were 0.03125 to approximately 0.5 mg/ml. SN - 1001-4454 UR - https://www.unboundmedicine.com/medline/citation/15307685/[Studies_on_antibacterial_activities_of_secondary_metabolites_from_fungus_Cephalosporium_sp__AL031]_ L2 - https://medlineplus.gov/antibiotics.html DB - PRIME DP - Unbound Medicine ER -