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Macrolides and ketolides: azithromycin, clarithromycin, telithromycin.
Infect Dis Clin North Am. 2004 Sep; 18(3):621-49, xi-.ID

Abstract

The advanced macrolides, azithromycin and clarithromycin, and the ketolide telithromycin are structural analogues of erythromycin. They have several distinct advantages when compared with erythromycin including enhanced spectrum of activity, more favorable pharmacokinetics and pharmacodynamics, once daily administration, and improved tolerability. This article reviews the pharmacokinetics, antimicrobial activity, clinical use, and adverse effects of these antimicrobial agents.

Authors+Show Affiliations

Jefferson Medical College, Philadelphia, PA, USA. zuckermj@einstein.edu

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15308279

Citation

Zuckerman, Jerry M.. "Macrolides and Ketolides: Azithromycin, Clarithromycin, Telithromycin." Infectious Disease Clinics of North America, vol. 18, no. 3, 2004, pp. 621-49, xi-.
Zuckerman JM. Macrolides and ketolides: azithromycin, clarithromycin, telithromycin. Infect Dis Clin North Am. 2004;18(3):621-49, xi-.
Zuckerman, J. M. (2004). Macrolides and ketolides: azithromycin, clarithromycin, telithromycin. Infectious Disease Clinics of North America, 18(3), 621-49, xi-.
Zuckerman JM. Macrolides and Ketolides: Azithromycin, Clarithromycin, Telithromycin. Infect Dis Clin North Am. 2004;18(3):621-49, xi-. PubMed PMID: 15308279.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Macrolides and ketolides: azithromycin, clarithromycin, telithromycin. A1 - Zuckerman,Jerry M, PY - 2004/8/17/pubmed PY - 2004/12/16/medline PY - 2004/8/17/entrez SP - 621-49, xi- JF - Infectious disease clinics of North America JO - Infect Dis Clin North Am VL - 18 IS - 3 N2 - The advanced macrolides, azithromycin and clarithromycin, and the ketolide telithromycin are structural analogues of erythromycin. They have several distinct advantages when compared with erythromycin including enhanced spectrum of activity, more favorable pharmacokinetics and pharmacodynamics, once daily administration, and improved tolerability. This article reviews the pharmacokinetics, antimicrobial activity, clinical use, and adverse effects of these antimicrobial agents. SN - 0891-5520 UR - https://www.unboundmedicine.com/medline/citation/15308279/Macrolides_and_ketolides:_azithromycin_clarithromycin_telithromycin_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0891552004000716 DB - PRIME DP - Unbound Medicine ER -