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Effect of a silicone intraocular lens with a sharp posterior optic edge on posterior capsule opacification.
J Cataract Refract Surg. 2004 Aug; 30(8):1661-7.JC

Abstract

PURPOSE

To compare the inhibiting effect on posterior capsule opacification (PCO) of a silicone intraocular lens (IOL) with a sharp posterior optic edge (ClariFlex OptiEdge, Advanced Medical Optics) and a silicone IOL with a round optic edge (PhacoFlex SI-40, Advanced Medical Optics).

SETTING

Department of Ophthalmology, University of Vienna, Vienna, Austria.

METHODS

This prospective randomized patient- and examiner-masked study comprised 104 eyes of 52 patients with bilateral age-related cataract. All patients had cataract surgery in both eyes and received a sharp-edged IOL in 1 eye and a round-edged IOL in the other eye. Postoperative examinations were at 1 week, 1 and 6 months, and 1 year. Digital slitlamp and retroillumination images were taken of each eye. The amount of PCO was assessed subjectively at the slitlamp and objectively using Automated Quantification of After-Cataract (AQUA) automated-image analysis software.

RESULTS

The sharp-edged IOL group had significantly less regeneratory and fibrotic PCO 1 month, 6 months, and 1 year after surgery. The mean AQUA PCO score (scale 0 to 10) was 0.71 in the sharp-edged IOL group and 1.40 in the round-edged IOL group (P<.001). The sharp-edged IOL group had less peripheral fibrotic PCO. There was no significant difference between the 2 IOL groups in patient reports of edge glare.

CONCLUSION

The sharp-edged design of the ClariFlex OptiEdge silicone IOL led to significantly less PCO than the round-edged PhacoFlex SI-40 IOL 1 year postoperatively.

Authors+Show Affiliations

Department of Ophthalmology, University of Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

15313288

Citation

Buehl, Wolf, et al. "Effect of a Silicone Intraocular Lens With a Sharp Posterior Optic Edge On Posterior Capsule Opacification." Journal of Cataract and Refractive Surgery, vol. 30, no. 8, 2004, pp. 1661-7.
Buehl W, Menapace R, Sacu S, et al. Effect of a silicone intraocular lens with a sharp posterior optic edge on posterior capsule opacification. J Cataract Refract Surg. 2004;30(8):1661-7.
Buehl, W., Menapace, R., Sacu, S., Kriechbaum, K., Koeppl, C., Wirtitsch, M., Georgopoulos, M., & Findl, O. (2004). Effect of a silicone intraocular lens with a sharp posterior optic edge on posterior capsule opacification. Journal of Cataract and Refractive Surgery, 30(8), 1661-7.
Buehl W, et al. Effect of a Silicone Intraocular Lens With a Sharp Posterior Optic Edge On Posterior Capsule Opacification. J Cataract Refract Surg. 2004;30(8):1661-7. PubMed PMID: 15313288.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of a silicone intraocular lens with a sharp posterior optic edge on posterior capsule opacification. AU - Buehl,Wolf, AU - Menapace,Rupert, AU - Sacu,Stefan, AU - Kriechbaum,Katharina, AU - Koeppl,Christina, AU - Wirtitsch,Matthias, AU - Georgopoulos,Michael, AU - Findl,Oliver, PY - 2003/12/18/accepted PY - 2004/8/18/pubmed PY - 2004/10/8/medline PY - 2004/8/18/entrez SP - 1661 EP - 7 JF - Journal of cataract and refractive surgery JO - J Cataract Refract Surg VL - 30 IS - 8 N2 - PURPOSE: To compare the inhibiting effect on posterior capsule opacification (PCO) of a silicone intraocular lens (IOL) with a sharp posterior optic edge (ClariFlex OptiEdge, Advanced Medical Optics) and a silicone IOL with a round optic edge (PhacoFlex SI-40, Advanced Medical Optics). SETTING: Department of Ophthalmology, University of Vienna, Vienna, Austria. METHODS: This prospective randomized patient- and examiner-masked study comprised 104 eyes of 52 patients with bilateral age-related cataract. All patients had cataract surgery in both eyes and received a sharp-edged IOL in 1 eye and a round-edged IOL in the other eye. Postoperative examinations were at 1 week, 1 and 6 months, and 1 year. Digital slitlamp and retroillumination images were taken of each eye. The amount of PCO was assessed subjectively at the slitlamp and objectively using Automated Quantification of After-Cataract (AQUA) automated-image analysis software. RESULTS: The sharp-edged IOL group had significantly less regeneratory and fibrotic PCO 1 month, 6 months, and 1 year after surgery. The mean AQUA PCO score (scale 0 to 10) was 0.71 in the sharp-edged IOL group and 1.40 in the round-edged IOL group (P<.001). The sharp-edged IOL group had less peripheral fibrotic PCO. There was no significant difference between the 2 IOL groups in patient reports of edge glare. CONCLUSION: The sharp-edged design of the ClariFlex OptiEdge silicone IOL led to significantly less PCO than the round-edged PhacoFlex SI-40 IOL 1 year postoperatively. SN - 0886-3350 UR - https://www.unboundmedicine.com/medline/citation/15313288/Effect_of_a_silicone_intraocular_lens_with_a_sharp_posterior_optic_edge_on_posterior_capsule_opacification_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0886335004002354 DB - PRIME DP - Unbound Medicine ER -