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[Indirect relation between intimo-medial thickness of the carotid artery and vasodilation of the popliteal artery].
Sb Lek. 2003; 104(4):361-8.SL

Abstract

BACKGROUND

Intima-media thickness of the common carotid artery (IMT ACC) and flow-mediated vasodilatation (FMD) of the brachial artery is considered an early marker of atherosclerosis. This study was undertaken to elucidate whether endothelial dysfunction in the popliteal artery, pronoun to atherosclerosis, is related to IMT ACC.

METHODS AND RESULTS

Twenty-nine control subjects, 29 asymptomatic patients with hyperlipoproteinemia (without therapy) and 26 patients with coronary artery disease were examined. Using ultrasound with a linear-array probe (7.5 MHz), we measured IMT ACC and diameter of the popliteal artery (PA) at rest and during reactive hyperaemia after release of 5-minute arterial occlusion. In control subjects we found thicker IMT ACC and greater FMD than did the patients (p<0.001, ANOVA test). A significant negative correlation between the IMT ACC and percent FMD was found in all of the subjects (p<0.001). On multiple regression analysis, percent FMD showed a significant negative correlation with the IMT ACC, total cholesterol, triacylglyceroles, body mass index, age, and diastolic blood pressure.

CONCLUSION

We found significant negative correlation between IMT common carotid artery and FMD popliteal artery.

Authors+Show Affiliations

III. interní klinika 1, lékarské fakulty Univerzity Karlovy a Vseobecné fakultní nemocnice v Praze.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

cze

PubMed ID

15320527

Citation

Spácil, J, et al. "[Indirect Relation Between Intimo-medial Thickness of the Carotid Artery and Vasodilation of the Popliteal Artery]." Sbornik Lekarsky, vol. 104, no. 4, 2003, pp. 361-8.
Spácil J, Ceska R, Haas T. [Indirect relation between intimo-medial thickness of the carotid artery and vasodilation of the popliteal artery]. Sb Lek. 2003;104(4):361-8.
Spácil, J., Ceska, R., & Haas, T. (2003). [Indirect relation between intimo-medial thickness of the carotid artery and vasodilation of the popliteal artery]. Sbornik Lekarsky, 104(4), 361-8.
Spácil J, Ceska R, Haas T. [Indirect Relation Between Intimo-medial Thickness of the Carotid Artery and Vasodilation of the Popliteal Artery]. Sb Lek. 2003;104(4):361-8. PubMed PMID: 15320527.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Indirect relation between intimo-medial thickness of the carotid artery and vasodilation of the popliteal artery]. AU - Spácil,J, AU - Ceska,R, AU - Haas,T, PY - 2004/8/24/pubmed PY - 2005/9/24/medline PY - 2004/8/24/entrez SP - 361 EP - 8 JF - Sbornik lekarsky JO - Sb Lek VL - 104 IS - 4 N2 - BACKGROUND: Intima-media thickness of the common carotid artery (IMT ACC) and flow-mediated vasodilatation (FMD) of the brachial artery is considered an early marker of atherosclerosis. This study was undertaken to elucidate whether endothelial dysfunction in the popliteal artery, pronoun to atherosclerosis, is related to IMT ACC. METHODS AND RESULTS: Twenty-nine control subjects, 29 asymptomatic patients with hyperlipoproteinemia (without therapy) and 26 patients with coronary artery disease were examined. Using ultrasound with a linear-array probe (7.5 MHz), we measured IMT ACC and diameter of the popliteal artery (PA) at rest and during reactive hyperaemia after release of 5-minute arterial occlusion. In control subjects we found thicker IMT ACC and greater FMD than did the patients (p<0.001, ANOVA test). A significant negative correlation between the IMT ACC and percent FMD was found in all of the subjects (p<0.001). On multiple regression analysis, percent FMD showed a significant negative correlation with the IMT ACC, total cholesterol, triacylglyceroles, body mass index, age, and diastolic blood pressure. CONCLUSION: We found significant negative correlation between IMT common carotid artery and FMD popliteal artery. SN - 0036-5327 UR - https://www.unboundmedicine.com/medline/citation/15320527/[Indirect_relation_between_intimo_medial_thickness_of_the_carotid_artery_and_vasodilation_of_the_popliteal_artery]_ DB - PRIME DP - Unbound Medicine ER -