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In vitro activity of voriconazole against Candida species isolated in Taiwan.
Int J Antimicrob Agents. 2004 Sep; 24(3):294-6.IJ

Abstract

The activity of voriconazole was determined against 285 Candida species consisting of 53 resistant isolates, 43 susceptible-dose dependent and 189 isolates susceptible to fluconazole. The MIC(50) and MIC(90) to fluconazole were 8 and 64 mg/l, respectively. The range of minimum inhibitory concentrations (MICs) to voriconazole was from 0.0325 to 2 mg/l and the MIC(50) and MIC(90) were 0.125 and 0.5 mg/l, respectively. Only 3 of 285 tested isolates had MICs to voriconazole equal to 2 mg/l. A total of 38 isolates, consisted of 3 Candida albicans, 5 Candida krusei, 7 Candida tropicalis and 21 Candida glabrata, had >/= 0.5 mg/l to voriconazole. There was correlation between the susceptibility to fluconazole and voriconazole.

Authors+Show Affiliations

Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan, ROC.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15325436

Citation

Yang, Yun-Liang, et al. "In Vitro Activity of Voriconazole Against Candida Species Isolated in Taiwan." International Journal of Antimicrobial Agents, vol. 24, no. 3, 2004, pp. 294-6.
Yang YL, Cheng HH, Lo HJ. In vitro activity of voriconazole against Candida species isolated in Taiwan. Int J Antimicrob Agents. 2004;24(3):294-6.
Yang, Y. L., Cheng, H. H., & Lo, H. J. (2004). In vitro activity of voriconazole against Candida species isolated in Taiwan. International Journal of Antimicrobial Agents, 24(3), 294-6.
Yang YL, Cheng HH, Lo HJ. In Vitro Activity of Voriconazole Against Candida Species Isolated in Taiwan. Int J Antimicrob Agents. 2004;24(3):294-6. PubMed PMID: 15325436.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - In vitro activity of voriconazole against Candida species isolated in Taiwan. AU - Yang,Yun-Liang, AU - Cheng,Hsiao-Hsu, AU - Lo,Hsiu-Jung, PY - 2003/09/30/received PY - 2004/01/09/accepted PY - 2004/8/25/pubmed PY - 2005/2/19/medline PY - 2004/8/25/entrez SP - 294 EP - 6 JF - International journal of antimicrobial agents JO - Int J Antimicrob Agents VL - 24 IS - 3 N2 - The activity of voriconazole was determined against 285 Candida species consisting of 53 resistant isolates, 43 susceptible-dose dependent and 189 isolates susceptible to fluconazole. The MIC(50) and MIC(90) to fluconazole were 8 and 64 mg/l, respectively. The range of minimum inhibitory concentrations (MICs) to voriconazole was from 0.0325 to 2 mg/l and the MIC(50) and MIC(90) were 0.125 and 0.5 mg/l, respectively. Only 3 of 285 tested isolates had MICs to voriconazole equal to 2 mg/l. A total of 38 isolates, consisted of 3 Candida albicans, 5 Candida krusei, 7 Candida tropicalis and 21 Candida glabrata, had >/= 0.5 mg/l to voriconazole. There was correlation between the susceptibility to fluconazole and voriconazole. SN - 0924-8579 UR - https://www.unboundmedicine.com/medline/citation/15325436/In_vitro_activity_of_voriconazole_against_Candida_species_isolated_in_Taiwan_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0924857904001608 DB - PRIME DP - Unbound Medicine ER -