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[Maternal morbidity and mortality in HELLP Syndrome].
Ginecol Obstet Mex. 2001 May; 69:189-93.GO

Abstract

OBJECTIVE

To describe the maternal morbidity and mortality in pregnancies complicated by HELLP Syndrome.

STUDY DESIGN

This is a descriptive and prospective study of women with HELLP Syndrome managed at our center from January 1998 through March 2000. Patients are grouped into 3-class system of Mississippi classification.

RESULTS

170 cases were analysed, 156 (92%), ocurred ante partum and 14 (8%) postpartum; 15 cases (9%) developed at < 27 weeks, 112 (66%) between 28 to 36 weeks of gestational age and 43 (25%) at term. Maternal morbidity included acute renal failure (13.5%), abruptio placentae (6.6%), pneumonia (3%), subcapsular liver hematoma (2.3%), pulmonary edema (2.3%), diseminated intravascular coagulopathy (1.7%) and cerebral hemorrhage (1.2%). Maternal mortality was 4.7% (8 patients), 7 deaths ocurred in patients with class I disease and only one with class II HELLP Syndrome. 6 maternal deaths (75%) were associated to eclampsia. Up to 85% of the maternal morbidity and mortality developed with class I disease (platelet nadir < 50,000 mm3.

CONCLUSIONS

There is a progressive rise in maternal morbidity and mortality as the pregnancy moves from class III to class I HELLP Syndrome. 75% of maternal mortality was associated with eclampsia. Early diagnosis of this syndrome could improve maternal prognosis and outcome.

Authors+Show Affiliations

Servicio de Complicaciones Hipertensivas del Embarazo, Hospital de Ginecoobstetricia Núm. 4 Luis Castelazo Ayala, IMSS.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

15326805

Citation

Romero Arauz, J F., et al. "[Maternal Morbidity and Mortality in HELLP Syndrome]." Ginecologia Y Obstetricia De Mexico, vol. 69, 2001, pp. 189-93.
Romero Arauz JF, Lara González AL, Ramos León JC, et al. [Maternal morbidity and mortality in HELLP Syndrome]. Ginecol Obstet Mex. 2001;69:189-93.
Romero Arauz, J. F., Lara González, A. L., Ramos León, J. C., & Izquierdo Puente, J. C. (2001). [Maternal morbidity and mortality in HELLP Syndrome]. Ginecologia Y Obstetricia De Mexico, 69, 189-93.
Romero Arauz JF, et al. [Maternal Morbidity and Mortality in HELLP Syndrome]. Ginecol Obstet Mex. 2001;69:189-93. PubMed PMID: 15326805.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Maternal morbidity and mortality in HELLP Syndrome]. AU - Romero Arauz,J F, AU - Lara González,A L, AU - Ramos León,J C, AU - Izquierdo Puente,J C, PY - 2004/8/26/pubmed PY - 2004/9/17/medline PY - 2004/8/26/entrez SP - 189 EP - 93 JF - Ginecologia y obstetricia de Mexico JO - Ginecol Obstet Mex VL - 69 N2 - OBJECTIVE: To describe the maternal morbidity and mortality in pregnancies complicated by HELLP Syndrome. STUDY DESIGN: This is a descriptive and prospective study of women with HELLP Syndrome managed at our center from January 1998 through March 2000. Patients are grouped into 3-class system of Mississippi classification. RESULTS: 170 cases were analysed, 156 (92%), ocurred ante partum and 14 (8%) postpartum; 15 cases (9%) developed at < 27 weeks, 112 (66%) between 28 to 36 weeks of gestational age and 43 (25%) at term. Maternal morbidity included acute renal failure (13.5%), abruptio placentae (6.6%), pneumonia (3%), subcapsular liver hematoma (2.3%), pulmonary edema (2.3%), diseminated intravascular coagulopathy (1.7%) and cerebral hemorrhage (1.2%). Maternal mortality was 4.7% (8 patients), 7 deaths ocurred in patients with class I disease and only one with class II HELLP Syndrome. 6 maternal deaths (75%) were associated to eclampsia. Up to 85% of the maternal morbidity and mortality developed with class I disease (platelet nadir < 50,000 mm3. CONCLUSIONS: There is a progressive rise in maternal morbidity and mortality as the pregnancy moves from class III to class I HELLP Syndrome. 75% of maternal mortality was associated with eclampsia. Early diagnosis of this syndrome could improve maternal prognosis and outcome. SN - 0300-9041 UR - https://www.unboundmedicine.com/medline/citation/15326805/[Maternal_morbidity_and_mortality_in_HELLP_Syndrome]_ L2 - https://www.diseaseinfosearch.org/result/3266 DB - PRIME DP - Unbound Medicine ER -