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Xanthelasma and lipoma in Leonardo da Vinci's Mona Lisa.
Isr Med Assoc J. 2004 Aug; 6(8):505-6.IM

Abstract

The painting Mona Lisa in the Louvre, Paris, by Leonardo da Vinci (1503-1506), shows skin alterations at the inner end of the left upper eyelid similar to xanthelasma, and a swelling of the dorsum of the right hand suggestive of a subcutaneous lipoma. These findings in a 25-30 year old woman, who died at the age of 37, may be indicative of essential hyperlipidemia, a strong risk factor for ischemic heart disease in middle age. As far as is known, this portrait of Mona Lisa painted in 1506 is the first evidence that xanthelasma and lipoma were prevalent in the sixteenth century, long before the first description by Addison and Gall in 1851.

Authors+Show Affiliations

Dequeker J
Department of Rheumatology, University Hospitals, KU Leuven, Belgium. jan.dequeker@med.kuleuven.ac.be
Muls E
No affiliation info available
Leenders K
No affiliation info available

MeSH

Eyelid DiseasesFamous PersonsFemaleHandHistory, 16th CenturyHumansHyperlipidemiasLipomaMedicine in the ArtsPaintingsXanthomatosis

Pub Type(s)

Biography
Historical Article
Journal Article
Portrait

Language

eng

PubMed ID

15326839

Citation

Dequeker, Jan, et al. "Xanthelasma and Lipoma in Leonardo Da Vinci's Mona Lisa." The Israel Medical Association Journal : IMAJ, vol. 6, no. 8, 2004, pp. 505-6.
Dequeker J, Muls E, Leenders K. Xanthelasma and lipoma in Leonardo da Vinci's Mona Lisa. Isr Med Assoc J. 2004;6(8):505-6.
Dequeker, J., Muls, E., & Leenders, K. (2004). Xanthelasma and lipoma in Leonardo da Vinci's Mona Lisa. The Israel Medical Association Journal : IMAJ, 6(8), 505-6.
Dequeker J, Muls E, Leenders K. Xanthelasma and Lipoma in Leonardo Da Vinci's Mona Lisa. Isr Med Assoc J. 2004;6(8):505-6. PubMed PMID: 15326839.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Xanthelasma and lipoma in Leonardo da Vinci's Mona Lisa. AU - Dequeker,Jan, AU - Muls,Erik, AU - Leenders,Kathleen, PY - 2004/8/26/pubmed PY - 2004/9/24/medline PY - 2004/8/26/entrez SP - 505 EP - 6 JF - The Israel Medical Association journal : IMAJ JO - Isr Med Assoc J VL - 6 IS - 8 N2 - The painting Mona Lisa in the Louvre, Paris, by Leonardo da Vinci (1503-1506), shows skin alterations at the inner end of the left upper eyelid similar to xanthelasma, and a swelling of the dorsum of the right hand suggestive of a subcutaneous lipoma. These findings in a 25-30 year old woman, who died at the age of 37, may be indicative of essential hyperlipidemia, a strong risk factor for ischemic heart disease in middle age. As far as is known, this portrait of Mona Lisa painted in 1506 is the first evidence that xanthelasma and lipoma were prevalent in the sixteenth century, long before the first description by Addison and Gall in 1851. SN - 1565-1088 UR - https://www.unboundmedicine.com/medline/citation/15326839/Xanthelasma_and_lipoma_in_Leonardo_da_Vinci's_Mona_Lisa_ DB - PRIME DP - Unbound Medicine ER -