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[Water-soluble chemical constituents of Swertia davidi Franch].
Yao Xue Xue Bao. 2004 May; 39(5):351-3.YX

Abstract

AIM

To study the active constituents of Swertia davidi Franch.

METHODS

Column chromatographies on silica gel, Sephadex LH-20 and Diaion-201 et al. were used to isolate and purify the chemical components. Their structures were identified by UV, IR, MS, NMR and 2D-NMR.

RESULTS

These compounds were elucidated as 8-O-beta-D-glucopyranosyl-1, 3, 5-trihydroxyxanthone (I), 5-O-beta-D-glucopyranosyl-1, 8-dihydroxy-3-methoxyxanthone (II), 5-O-beta-D-glucopyranosyl-1, 3, 8-trihydroxyxanthone (III) and swertamarin (IV).

CONCLUSION

Compound III is a new xanthone glucoside. The other compounds were isolated from this plant for the first time.

Authors+Show Affiliations

Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

15338877

Citation

Zeng, Guang-yao, et al. "[Water-soluble Chemical Constituents of Swertia Davidi Franch]." Yao Xue Xue Bao = Acta Pharmaceutica Sinica, vol. 39, no. 5, 2004, pp. 351-3.
Zeng GY, Tan GS, Xu KP, et al. [Water-soluble chemical constituents of Swertia davidi Franch]. Yao Xue Xue Bao. 2004;39(5):351-3.
Zeng, G. Y., Tan, G. S., Xu, K. P., Xu, X. P., Li, F. S., Tan, J. B., & Hu, G. Y. (2004). [Water-soluble chemical constituents of Swertia davidi Franch]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica, 39(5), 351-3.
Zeng GY, et al. [Water-soluble Chemical Constituents of Swertia Davidi Franch]. Yao Xue Xue Bao. 2004;39(5):351-3. PubMed PMID: 15338877.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Water-soluble chemical constituents of Swertia davidi Franch]. AU - Zeng,Guang-yao, AU - Tan,Gui-shan, AU - Xu,Kang-ping, AU - Xu,Xiao-ping, AU - Li,Fu-shuang, AU - Tan,Jian-bing, AU - Hu,Gao-yun, PY - 2004/9/2/pubmed PY - 2004/12/16/medline PY - 2004/9/2/entrez SP - 351 EP - 3 JF - Yao xue xue bao = Acta pharmaceutica Sinica JO - Yao Xue Xue Bao VL - 39 IS - 5 N2 - AIM: To study the active constituents of Swertia davidi Franch. METHODS: Column chromatographies on silica gel, Sephadex LH-20 and Diaion-201 et al. were used to isolate and purify the chemical components. Their structures were identified by UV, IR, MS, NMR and 2D-NMR. RESULTS: These compounds were elucidated as 8-O-beta-D-glucopyranosyl-1, 3, 5-trihydroxyxanthone (I), 5-O-beta-D-glucopyranosyl-1, 8-dihydroxy-3-methoxyxanthone (II), 5-O-beta-D-glucopyranosyl-1, 3, 8-trihydroxyxanthone (III) and swertamarin (IV). CONCLUSION: Compound III is a new xanthone glucoside. The other compounds were isolated from this plant for the first time. SN - 0513-4870 UR - https://www.unboundmedicine.com/medline/citation/15338877/[Water_soluble_chemical_constituents_of_Swertia_davidi_Franch]_ DB - PRIME DP - Unbound Medicine ER -