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Suitability of soluble transferrin receptor for the clinical diagnosis of different types of anaemia in children.
East Mediterr Health J 2002 Mar-May; 8(2-3):298-307EM

Abstract

We evaluated the ability of serum transferrin receptor (sTFR) to identify different types of anaemia in children. Thus 150 Egyptian children suffering from anaemia (iron deficiency anaemia, anaemia of chronic disease and beta-thalassaemia) were enrolled, together with 50 controls. There was a significant increase in the mean levels of sTFR in the groups with iron deficiency anaemia and thalassaemia, and a significant decrease in mean sTFR levels in the group with anaemia of chronic disease. Serum ferritin levels were significantly higher in all patient groups except the group with iron deficiency anaemia. There were also significant correlations between the sTFR and sTFR/log ferritin ratio (sTFR-F index) and different indices of iron status and of erythropoiesis. The sTFR-F index could be used as a diagnostic or screening tool for iron deficiency anaemia, anaemia of chronic disease and thalassaemia.

Authors+Show Affiliations

Department of Paediatrics, Faculty of Medicine, University of Cairo, Cairo, Egypt.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Validation Study

Language

eng

PubMed ID

15339117

Citation

Ragab, L, et al. "Suitability of Soluble Transferrin Receptor for the Clinical Diagnosis of Different Types of Anaemia in Children." Eastern Mediterranean Health Journal = La Revue De Sante De La Mediterranee Orientale = al-Majallah Al-sihhiyah Li-sharq Al-mutawassit, vol. 8, no. 2-3, 2002, pp. 298-307.
Ragab L, Ibrahim HA, Eid AS, et al. Suitability of soluble transferrin receptor for the clinical diagnosis of different types of anaemia in children. East Mediterr Health J. 2002;8(2-3):298-307.
Ragab, L., Ibrahim, H. A., Eid, A. S., Kotb, T., & Konsowa, M. F. (2002). Suitability of soluble transferrin receptor for the clinical diagnosis of different types of anaemia in children. Eastern Mediterranean Health Journal = La Revue De Sante De La Mediterranee Orientale = al-Majallah Al-sihhiyah Li-sharq Al-mutawassit, 8(2-3), pp. 298-307.
Ragab L, et al. Suitability of Soluble Transferrin Receptor for the Clinical Diagnosis of Different Types of Anaemia in Children. East Mediterr Health J. 2002;8(2-3):298-307. PubMed PMID: 15339117.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Suitability of soluble transferrin receptor for the clinical diagnosis of different types of anaemia in children. AU - Ragab,L, AU - Ibrahim,H A, AU - Eid,A S, AU - Kotb,T, AU - Konsowa,M F, PY - 2004/9/2/pubmed PY - 2004/10/23/medline PY - 2004/9/2/entrez SP - 298 EP - 307 JF - Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit JO - East. Mediterr. Health J. VL - 8 IS - 2-3 N2 - We evaluated the ability of serum transferrin receptor (sTFR) to identify different types of anaemia in children. Thus 150 Egyptian children suffering from anaemia (iron deficiency anaemia, anaemia of chronic disease and beta-thalassaemia) were enrolled, together with 50 controls. There was a significant increase in the mean levels of sTFR in the groups with iron deficiency anaemia and thalassaemia, and a significant decrease in mean sTFR levels in the group with anaemia of chronic disease. Serum ferritin levels were significantly higher in all patient groups except the group with iron deficiency anaemia. There were also significant correlations between the sTFR and sTFR/log ferritin ratio (sTFR-F index) and different indices of iron status and of erythropoiesis. The sTFR-F index could be used as a diagnostic or screening tool for iron deficiency anaemia, anaemia of chronic disease and thalassaemia. SN - 1020-3397 UR - https://www.unboundmedicine.com/medline/citation/15339117/Suitability_of_soluble_transferrin_receptor_for_the_clinical_diagnosis_of_different_types_of_anaemia_in_children_ L2 - http://applications.emro.who.int/emhj/0802_3/emhj_2002_8_2_3_298_307.pdf DB - PRIME DP - Unbound Medicine ER -