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[Visiting high altitudes--healthy persons and patients with risk diseases].
MMW Fortschr Med. 2004 Feb 19; 146(8):33-4, 36-7.MF

Abstract

At altitudes higher than the threshold altitude of 2,500 m, high-altitude diseases may occur, usually after a delay of 6 to 12 hours. Apart from the headache associated with acute mountain sickness, life-threatening cerebral edema may develop. High-altitude pulmonary edema is a non-cardiac edema that often precedes acute mountain sickness. The most important preventive measure is a slow ascent. In the case of mountain sickness a prophylactic effect can be achieved with acetazolamide or dexamethasone possible, while for high-altitude pulmonary edema, nifedipine is the first-choice drug. Immediate descent and the administration of oxygen are always indicated. Patients with a high-altitude risk are those with cardiac or pulmonary disease. Nevertheless, it is still possible for patients with coronary heart disease, hypertension or bronchial asthma to attain to high altitudes. In contrast, patients with COPD, interstitial pulmonary disease or pulmonary hypertension are at appreciably greater risk.

Authors+Show Affiliations

Fischer R
Deutschen Gesellschaft für Berg- und Expeditionsmedizin, Medizinische Klinik Innenstadt, Universität München. Rainald.Fischer@med.uni-muenchen.de

MeSH

AcclimatizationAcetazolamideAcute DiseaseAltitudeAltitude SicknessAnti-Inflammatory AgentsAsthmaBrain EdemaCalcium Channel BlockersCarbonic Anhydrase InhibitorsDexamethasoneHumansHypertensionNifedipineOxygenPulmonary Disease, Chronic ObstructivePulmonary EdemaPulmonary EmphysemaRisk FactorsTime FactorsVasodilator Agents

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Review

Language

ger

PubMed ID

15346935

Citation

Fischer, R. "[Visiting High Altitudes--healthy Persons and Patients With Risk Diseases]." MMW Fortschritte Der Medizin, vol. 146, no. 8, 2004, pp. 33-4, 36-7.
Fischer R. [Visiting high altitudes--healthy persons and patients with risk diseases]. MMW Fortschr Med. 2004;146(8):33-4, 36-7.
Fischer, R. (2004). [Visiting high altitudes--healthy persons and patients with risk diseases]. MMW Fortschritte Der Medizin, 146(8), 33-4, 36-7.
Fischer R. [Visiting High Altitudes--healthy Persons and Patients With Risk Diseases]. MMW Fortschr Med. 2004 Feb 19;146(8):33-4, 36-7. PubMed PMID: 15346935.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Visiting high altitudes--healthy persons and patients with risk diseases]. A1 - Fischer,R, PY - 2004/9/7/pubmed PY - 2004/10/1/medline PY - 2004/9/7/entrez SP - 33-4, 36-7 JF - MMW Fortschritte der Medizin JO - MMW Fortschr Med VL - 146 IS - 8 N2 - At altitudes higher than the threshold altitude of 2,500 m, high-altitude diseases may occur, usually after a delay of 6 to 12 hours. Apart from the headache associated with acute mountain sickness, life-threatening cerebral edema may develop. High-altitude pulmonary edema is a non-cardiac edema that often precedes acute mountain sickness. The most important preventive measure is a slow ascent. In the case of mountain sickness a prophylactic effect can be achieved with acetazolamide or dexamethasone possible, while for high-altitude pulmonary edema, nifedipine is the first-choice drug. Immediate descent and the administration of oxygen are always indicated. Patients with a high-altitude risk are those with cardiac or pulmonary disease. Nevertheless, it is still possible for patients with coronary heart disease, hypertension or bronchial asthma to attain to high altitudes. In contrast, patients with COPD, interstitial pulmonary disease or pulmonary hypertension are at appreciably greater risk. SN - 1438-3276 UR - https://www.unboundmedicine.com/medline/citation/15346935/[Visiting_high_altitudes__healthy_persons_and_patients_with_risk_diseases]_ DB - PRIME DP - Unbound Medicine ER -