Citation
Lombardero, M, et al. "Prevalence of Sensitization to Artemisia Allergens Art V 1, Art V 3 and Art V 60 kDa. Cross-reactivity Among Art V 3 and Other Relevant Lipid-transfer Protein Allergens." Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology, vol. 34, no. 9, 2004, pp. 1415-21.
Lombardero M, García-Sellés FJ, Polo F, et al. Prevalence of sensitization to Artemisia allergens Art v 1, Art v 3 and Art v 60 kDa. Cross-reactivity among Art v 3 and other relevant lipid-transfer protein allergens. Clin Exp Allergy. 2004;34(9):1415-21.
Lombardero, M., García-Sellés, F. J., Polo, F., Jimeno, L., Chamorro, M. J., García-Casado, G., Sánchez-Monge, R., Díaz-Perales, A., Salcedo, G., & Barber, D. (2004). Prevalence of sensitization to Artemisia allergens Art v 1, Art v 3 and Art v 60 kDa. Cross-reactivity among Art v 3 and other relevant lipid-transfer protein allergens. Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology, 34(9), 1415-21.
Lombardero M, et al. Prevalence of Sensitization to Artemisia Allergens Art V 1, Art V 3 and Art V 60 kDa. Cross-reactivity Among Art V 3 and Other Relevant Lipid-transfer Protein Allergens. Clin Exp Allergy. 2004;34(9):1415-21. PubMed PMID: 15347375.
TY - JOUR
T1 - Prevalence of sensitization to Artemisia allergens Art v 1, Art v 3 and Art v 60 kDa. Cross-reactivity among Art v 3 and other relevant lipid-transfer protein allergens.
AU - Lombardero,M,
AU - García-Sellés,F J,
AU - Polo,F,
AU - Jimeno,L,
AU - Chamorro,M J,
AU - García-Casado,G,
AU - Sánchez-Monge,R,
AU - Díaz-Perales,A,
AU - Salcedo,G,
AU - Barber,D,
PY - 2004/9/7/pubmed
PY - 2005/2/8/medline
PY - 2004/9/7/entrez
SP - 1415
EP - 21
JF - Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
JO - Clin Exp Allergy
VL - 34
IS - 9
N2 - BACKGROUND: Artemisia vulgaris is a widespread weed in the Mediterranean area and several allergens have been detected in its pollen. One of them, Art v 3, belongs to the lipid-transfer protein (LTP) family and its prevalence in Artemisia-sensitized patients or its relationship with other LTP allergens is not clear. OBJECTIVE: To assess the pattern of sensitization to an array of mugwort allergens in a Mediterranean population, and to study the cross-reactivity of Art v 3 with Pru p 3 and Par j 1, relevant LTP allergens in the area. METHODS: Skin prick test was performed with whole extracts (A. vulgaris, Parietaria judaica and peach) and pure natural allergens Art v 1, Art v 3, Art v 60 kDa and Par j 1 in 24 mugwort-allergic patients from a Mediterranean area. In vitro assays included measurement of specific IgE and ELISA inhibition among LTP allergens. RESULTS: The three Artemisia allergens elicited a positive skin response in 70-80% of the patients. Seven patients were clearly sensitized to Par j 1 and 11 to Pru p 3. There was no correlation between Par j 1 and Pru p 3 sensitization, but a highly significant correlation was found between peach extract and Art v 3 as regards the skin response. No IgE cross-reactivity was observed between Art v 3/Par j 1 or Pru p 3/Par j 1. In contrast, Art v 3 significantly inhibited the binding to Pru p 3 of IgE from three patients' sera out of six studied, but Pru p 3 was not able to inhibit the IgE binding to Art v 3. CONCLUSION: Art v 3 is a major mugwort allergen and in some patients with IgE to both Art v 3 and Pru p 3, Art v 3 behaves as the primary sensitizing agent.
SN - 0954-7894
UR - https://www.unboundmedicine.com/medline/citation/15347375/Prevalence_of_sensitization_to_Artemisia_allergens_Art_v_1_Art_v_3_and_Art_v_60_kDa__Cross_reactivity_among_Art_v_3_and_other_relevant_lipid_transfer_protein_allergens_
L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0954-7894&date=2004&volume=34&issue=9&spage=1415
DB - PRIME
DP - Unbound Medicine
ER -