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The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study.
Ophthalmology 2004; 111(9):1641-8O

Abstract

PURPOSE

To assess the prevalence of primary open-angle glaucoma (POAG) and its association with intraocular pressure (IOP) in Tajimi City in central Japan.

DESIGN

A cross-sectional epidemiologic study in a defined population.

PARTICIPANTS

Subjects randomly selected from the population older than 40 years in Tajimi City.

INTERVENTION

Each subject underwent a screening examination comprised of an interview and ophthalmic examinations, including measurement of IOP by a Goldmann applanation tonometer, central corneal thickness (CCT), slit-lamp examination, fundus photography, and a screening visual field test using frequency doubling technology. When ocular diseases were suspected, the subjects were referred for definitive examination. During the definitive examination, slit-lamp examination, IOP measurement, a visual field test using Humphrey Field Analyzer 30-2 SITA Standard program (Humphrey Instruments, San Leandro, CA), optic disc and fundus examination, and gonioscopy were performed and stereoscopic disc photographs were obtained. A diagnosis of glaucoma was made based on optic disc appearance, perimetric results, and other ocular findings.

MAIN OUTCOME MEASURES

Prevalence of POAG, mean IOP, and mean CCT.

RESULTS

Of 3870 eligible people, 3021 (78.1%) participated in the study. The estimated prevalence of POAG in the population older than 40 years was 3.9% (95% confidence interval [CI]), 3.2%-4.6%). The prevalence of cases of POAG with IOP levels of 21 mmHg or less was 3.6% (95% CI, 2.9%-4.3%), whereas the prevalence for those with IOP levels of more than 21 mmHg was 0.3% (95% CI, 0.1%-0.5%). The average IOP for eyes with POAG was 15.4+/-2.8 (standard deviation) in the right eye (n = 115) and 15.2+/-2.8 mmHg in the left eye (n = 115), which was significantly higher than that of nonglaucoma subjects (14.5+/-2.5 in the right eye; n = 2759; P = 0.0004; and 14.4+/-2.6 mmHg in the left eye; n = 2757; P = 0.0026). The mean CCT of POAG eyes with IOP levels of 21 mmHg or less was 518+/-29 (n = 109) in the right eye and 519+/-29 microm (n = 110) in the left eye, levels that were not significantly different from that of nonglaucoma eyes (520+/-32 microm [n = 2690]; and 522+/-32 microm [n = 2692]; P>0.05).

CONCLUSIONS

The prevalence of POAG in this population was 3.9%. In 92% patients with POAG, the IOP was 21 mmHg or less.

Authors+Show Affiliations

Department of Ophthalmology, Tajimi Municipal Hospital, Tajimi, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15350316

Citation

Iwase, Aiko, et al. "The Prevalence of Primary Open-angle Glaucoma in Japanese: the Tajimi Study." Ophthalmology, vol. 111, no. 9, 2004, pp. 1641-8.
Iwase A, Suzuki Y, Araie M, et al. The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study. Ophthalmology. 2004;111(9):1641-8.
Iwase, A., Suzuki, Y., Araie, M., Yamamoto, T., Abe, H., Shirato, S., ... Kitazawa, Y. (2004). The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study. Ophthalmology, 111(9), pp. 1641-8.
Iwase A, et al. The Prevalence of Primary Open-angle Glaucoma in Japanese: the Tajimi Study. Ophthalmology. 2004;111(9):1641-8. PubMed PMID: 15350316.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study. AU - Iwase,Aiko, AU - Suzuki,Yasuyuki, AU - Araie,Makoto, AU - Yamamoto,Tetsuya, AU - Abe,Haruki, AU - Shirato,Shiroaki, AU - Kuwayama,Yasuaki, AU - Mishima,Hiromu K, AU - Shimizu,Hiroyuki, AU - Tomita,Goji, AU - Inoue,Yoichi, AU - Kitazawa,Yoshiaki, AU - ,, PY - 2003/05/27/received PY - 2004/03/12/accepted PY - 2004/9/8/pubmed PY - 2004/9/15/medline PY - 2004/9/8/entrez SP - 1641 EP - 8 JF - Ophthalmology JO - Ophthalmology VL - 111 IS - 9 N2 - PURPOSE: To assess the prevalence of primary open-angle glaucoma (POAG) and its association with intraocular pressure (IOP) in Tajimi City in central Japan. DESIGN: A cross-sectional epidemiologic study in a defined population. PARTICIPANTS: Subjects randomly selected from the population older than 40 years in Tajimi City. INTERVENTION: Each subject underwent a screening examination comprised of an interview and ophthalmic examinations, including measurement of IOP by a Goldmann applanation tonometer, central corneal thickness (CCT), slit-lamp examination, fundus photography, and a screening visual field test using frequency doubling technology. When ocular diseases were suspected, the subjects were referred for definitive examination. During the definitive examination, slit-lamp examination, IOP measurement, a visual field test using Humphrey Field Analyzer 30-2 SITA Standard program (Humphrey Instruments, San Leandro, CA), optic disc and fundus examination, and gonioscopy were performed and stereoscopic disc photographs were obtained. A diagnosis of glaucoma was made based on optic disc appearance, perimetric results, and other ocular findings. MAIN OUTCOME MEASURES: Prevalence of POAG, mean IOP, and mean CCT. RESULTS: Of 3870 eligible people, 3021 (78.1%) participated in the study. The estimated prevalence of POAG in the population older than 40 years was 3.9% (95% confidence interval [CI]), 3.2%-4.6%). The prevalence of cases of POAG with IOP levels of 21 mmHg or less was 3.6% (95% CI, 2.9%-4.3%), whereas the prevalence for those with IOP levels of more than 21 mmHg was 0.3% (95% CI, 0.1%-0.5%). The average IOP for eyes with POAG was 15.4+/-2.8 (standard deviation) in the right eye (n = 115) and 15.2+/-2.8 mmHg in the left eye (n = 115), which was significantly higher than that of nonglaucoma subjects (14.5+/-2.5 in the right eye; n = 2759; P = 0.0004; and 14.4+/-2.6 mmHg in the left eye; n = 2757; P = 0.0026). The mean CCT of POAG eyes with IOP levels of 21 mmHg or less was 518+/-29 (n = 109) in the right eye and 519+/-29 microm (n = 110) in the left eye, levels that were not significantly different from that of nonglaucoma eyes (520+/-32 microm [n = 2690]; and 522+/-32 microm [n = 2692]; P>0.05). CONCLUSIONS: The prevalence of POAG in this population was 3.9%. In 92% patients with POAG, the IOP was 21 mmHg or less. SN - 1549-4713 UR - https://www.unboundmedicine.com/medline/citation/15350316/The_prevalence_of_primary_open_angle_glaucoma_in_Japanese:_the_Tajimi_Study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0161-6420(04)00665-7 DB - PRIME DP - Unbound Medicine ER -